...BRCA1 expression. To understand transcriptional regulation of the BRCA1 gene, we cloned and examined the BRCA1 promoter,...
...BRCA1 has intrinsic transactivation activity and is able to activate the p21 promoter. In addition, BRCA1 is linked to a...
...BRCA1 mutations. However, the widespread use of BRCA1 testing has been limited to date by three principal concerns: the ...
...BRCA1 and BRCA2 genes has improved our understanding of the association between breast and ovarian cancers in certain fa...
...BRCA1 confer a high risk of breast and ovarian tumors. The role of BRCA1 in tumor suppression is not yet understood, but...
...BRCA1, COMT, CYP17, CYP1A1, NAT1, and NAT2, the best estimate of risk either from the individual studies or the meta-ana...
...BRCA1 DNA into blastocysts.,Hatching mouse blastocysts (N = 70) were incubated in the presence of either viable or dead ...
...BRCA1 gene. Although BRCA1 mediates multiple functions in the cell, including a role in DNA damage repair and gene trans...
...BRCA1 mutation carriers. This seems to indicate that BRCA1-related breast cancer is not associated with a survival advan...
...Brca1 in response to ionizing radiation. ATM resides in a complex with Brca1 and phosphorylated Brca1 in vivo and in vit...
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