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TP53 BRCA1 CRISPR single-cell cancer

Arnold(N),Gross(E),Schwarz-Boeger(U),Pfist... Hum Mutat 1999-11-05

...BRCA1 mutations were tested. Of 1,518 amplicons analyzed by DHPLC, corresponding to 33 fragments spanning the entire BRC...

Zhong(Q),Chen(C F),Li(S),Chen(Y),Wang(C C)... Science 1999-08-16

...BRCA1 but was restored by transfection of wild-type BRCA1. Ectopic expression of wild-type, but not mutated, BRCA1 in th...

Lallas(T A),Buekers(T E),Buller(R E) Mol Genet Metab 1999-09-22

BRCA1 mutation research in ovarian and breast cancer 17q21-linked families has yielded a large number of germline sequen...

Ingvarsson(S) Semin Cancer Biol 1999-10-07

...BRCA1 or BRCA2 gene have an increase of additional genetic defects compared with sporadic breast tumors. This higher fre...

Santarosa(M),Dolcetti(R),Magri(M D),Crivel... Int J Cancer 1999-09-10

...BRCA1 gene. The coding region and splice boundaries of BRCA2 and BRCA1 genes were assessed by the protein-truncation tes...

Jacquemier(J),Eisinger(F),Noguès(C),Sun(Z ... Int J Cancer 1999-09-10

...BRCA1-associated breast cancers (BRCA1-BCs), we investigated E-cadherin expression by immuno-histochemistry in a combine...

Angelopoulou(K),Borchert(G),Melegos(D N),L... Urology 1999-11-05

...BRCA1 protein. Our objective was to characterize the BRCA1-like immunoreactivity that is detected in human seminal plasm...

Papp(J),Raicevic(L),Milasin(J),Dimitrijevi... Oncol Rep 1999-12-07

...BRCA1 mutations determined in this panel of families confirms the important role of BRCA1 in disease predisposition in t...

Aprelikova(O N),Fang(B S),Meissner(E G),Co... Proc Natl Acad Sci U S A 1999-11-24

...BRCA1 inhibits growth of some but not all cell lines. In an attempt to uncover the mechanism of growth suppression by BR...

Chen(Y),Lee(W H),Chew(H K) J Cell Physiol 1999-11-26

...BRCA1 has intrinsic transactivation activity and is able to activate the p21 promoter. In addition, BRCA1 is linked to a...

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