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Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.

Zhang(X),Moréra(S),Bates(P A),Whitehead(P ... EMBO J 1999-01-11

...BRCA1 C-terminus), first identified in the breast cancer suppressor protein BRCA1, is an evolutionarily conserved protei...

BRCA1 and BRCA2 proteins: roles in health and disease.

Duncan(J A),Reeves(J R),Cooke(T G) Mol Pathol 1999-04-29

...BRCA1 and BRCA2. Since the sequencing of these genes, considerable research on the genetics of the mutation carriers has...

Rolling circle amplification of DNA immobilized on solid surfaces and its app...

Hatch(A),Sano(T),Misasi(J),Smith(C L) Genet Anal 1999-05-28

...BRCA1 exon 5. These results demonstrate that RCA offers considerable promise to facilitate effective mutation screening ...

Incidence of loss of heterozygosity at p53 and BRCA1 loci in serous surface c...

Quezado(M M),Moskaluk(C A),Bryant(B),Mills... Hum Pathol 1999-03-02

...BRCA1 gene are uncommon in sporadic ovarian cases. In contrast, germline BRCA1 mutations are responsible for some heredi...

Positive regulation of the BRCA1 promoter.

Thakur(S),Croce(C M) J Biol Chem 1999-04-29

...BRCA1 gene expression/function in breast cancers. Therefore, we initiated studies on the BRCA1 transcriptional promoter....

[Epidemiology of breast cancer].

Sancho-Garnier(H) Bull Acad Natl Med 1999-04-19

...Brca1, Brca2 ...) have been identified.

Characteristics of small breast and/or ovarian cancer families with germline ...

Ligtenberg(M J),Hogervorst(F B),Willems(H ... Br J Cancer 1999-04-15

...BRCA1 or BRCA2. In 104 families with three or more affected individuals (average 3.8) seeking counselling at family canc...

[Impact of recent oncogenetic progress on the management of high risk breast ...

Sobol(H),Eisinger(F),Sauvan(R),Noguchi(T),... Ann Endocrinol (Paris) 1999-04-22

...BRCA1-associated breast cancers appear as high grade, poorly differentiated, highly proliferating, and frequently estrog...

[INSERM-FNCLCC collective expert's report. Recommendations for management of ...

Eisinger(F),Alby(N),Bremond(A),Dauplat(J),... Ann Endocrinol (Paris) 1999-04-22

...BRCA1 and BRCA2 germline mutations. Despite the uncertainty, consensus guidelines were defined to assist practitioners',...

Mammary gland development, reproductive history, and breast cancer risk.

Chodosh(L A),D'Cruz(C M),Gardner(H P),Ha(S... Cancer Res 1999-04-22

...BRCA1 and BRCA2, in the normal differentiation and development of the breast; studying the function of three novel prote...

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