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TP53 BRCA1 CRISPR single-cell cancer

Frank(T S) Arch Pathol Lab Med 1999-11-30

Inherited mutations in the genes BRCA1 and BRCA2 are associated with a significantly increased risk of breast cancer, pa...

Schultz(L B),Weber(B L) Curr Opin Oncol 1999-12-03

...BRCA1, as has our knowledge of the role of the ATM gene and predisposition to breast cancer in ataxia-telangiectasia car...

Dunning(A M),Healey(C S),Pharoah(P D),Tear... Cancer Epidemiol Biomarkers... 1999-12-10

...BRCA1, COMT, CYP17, CYP1A1, NAT1, and NAT2, the best estimate of risk either from the individual studies or the meta-ana...

Cortez(D),Wang(Y),Qin(J),Elledge(S J) Science 1999-12-10

...Brca1 in response to ionizing radiation. ATM resides in a complex with Brca1 and phosphorylated Brca1 in vivo and in vit...

Zweemer(R P),Shaw(P A),Verheijen(R M),Ryan... J Clin Pathol 1999-11-16

...BRCA1 and BRCA2 germline mutations. BRCA1 related ovarian cancers showed p53 accumulation in 22 of 30 cases (73%); p53 a...

Bennett(L M) Mol Carcinog 1999-12-02

...BRCA1, BRCA2, ATM, and p53, has been accompanied by the examination of the effects of radiation in combination with gene...

Hopper(J L),Southey(M C),Dite(G S),Jolley(... Cancer Epidemiol Biomarkers... 1999-11-10

...BRCA1 and 9 BRCA2), only 5 (1 BRCA1 and 4 BRCA2) had at least one affected relative, so family history of breast cancer ...

Yamane(K),Tsuruo(T) Oncogene 1999-10-21

The BRCT region, the carboxyl-terminus of BRCA1 (the breast cancer susceptibility gene 1 product), is a ubiquitous regio...

Lorick(K L),Jensen(J P),Fang(S),Ong(A M),H... Proc Natl Acad Sci U S A 1999-10-21

...BRCA1, Siah-1, TRC8, NF-X1, kf-1, and Praja1, were assessed for their ability to facilitate E2-dependent ubiquitination....

Huusko(P),Castrén(K),Launonen(V),Soini(Y),... Cancer Genet Cytogenet 1999-08-18

Mutations in BRCA1 and BRCA2 account for a large portion of the inherited predisposition to breast and ovarian cancer. I...

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