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TP53 BRCA1 CRISPR single-cell cancer

Dørum(A),Heimdal(K),Hovig(E),Inganäs(M),Mø... Am J Hum Genet 1999-10-04

...BRCA1 founder mutations in the Norwegian population. Index cases for the present study were found two different ways: th...

Park(S J),Chan(P J),Seraj(I M),King(A) J Reprod Med 1999-10-21

To determine the integrity of the BRCA1 gene in archival, paraffin-embedded tissues from precancerous lesions of the ute...

Tait(D L),Obermiller(P S),Hatmaker(A R),Re... Clin Cancer Res 1999-09-22

...BRCA1sv gene therapy reported stable vector, minimal antibody response, and tumor reduction. We initiated a Phase II tri...

Frank(T S),Braverman(A M) Int J Fertil Womens Med 1999-10-26

Nearly 10% of breast and ovarian cancers develop as a direct consequence of an inherited flaw in the genes BRCA1 and BRC...

Trincado(P),Fardella(C),Mayerson(D),Monter... Rev Med Chil 1999-10-14

...BRCA1 gene. These are associated with familial breast cancer in up to 80% of cases. The most frequent mutation of BRCA1 ...

Khoo(U S),Ozcelik(H),Cheung(A N),Chow(L W)... Oncogene 1999-10-04

Inherited mutations in the BRCA1 gene confer increased susceptibility to breast and ovarian cancer. Its role in sporadic...

Loader(S),Levenkron(J C),Rowley(P T) Genet Test 1999-10-12

...BRCA1 or BRCA2 mutations were found in 13 of the 87 families actually tested. If the criteria for testing had been three...

Schubert(E L),Mefford(H C),Dann(J L),Argon... Genet Test 1999-09-28

...BRCA1 and BRCA2. Ancient mutations existed in 9 families; 7 had the BRCA1 185 del AG mutation, 1 had BRCA1 5382 ins C, a...

Robson(M),Dabney(M K),Rosenthal(G),Ludwig(... Genet Test 1999-09-28

...BRCA1 185delAG was the most common mutation overall (40/236, 16.9%). The ratio of BRCA1 185delAG to BRCA2 6174delT was 4...

Neuhausen(S L),Ostrander(E A) Genet Test 1999-09-28

BRCA1 and BRCA2, genes predisposing to early-onset breast cancer, have been isolated and are characterized for mutation ...

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