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Slx4 and Fun30/SMARCAD1 coordinate S-phase checkpoint regulation and replicatio…

Courtes(M),Boissière(T),Barthe(A),Pasero(P),… Nucleic Acids Res 2026-04-13

...Exo1-dependent resection of replication forks stalled by Top1-DNA crosslinks. Controlled resection, in turn, allows homo...

Strand-independent degradation of uncoupled forks by EXO1 activates ATR and res…

Grogan(EJ),Ozua(OE),Kavlashvili(T),Conwell(S… bioRxiv 2026-03-25

...EXO1 is critically important for degradation of uncoupled forks, independent of any degradation at reversed forks. Laggi...

Genetic and Molecular Mechanisms Linking Breast Cancer to Meningioma Risk: Role…

Lin(C),Hu(J),Cai(F),Chen(J),Huang(J),Lin(Y) Curr Med Chem 2026-03-18

...EXO1, BRCA2, and ESR1 as key hub genes. These genes were upregulated in tumors, showing robust diagnostic performance (A...

DNA repair-associated nucleases induce double-strand breaks following sequentia…

Narimichi(M),Komaki(Y),Suzuki(T),Ibuki(Y) Photochem Photobiol Sci 2026-04-00

...EXO1 and MRE11. Inhibition of MRE11 endonuclease activity with PFM01 suppressed DSB formation after sequential exposure ...

Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-a…

Nusawardhana(A),Hale(A),Straka(J),Nicolae(CM… Nucleic Acids Res 2026-02-24

...EXO1-deficient cells. We uncovered differential regulators of cisplatin sensitivity between wildtype (WT) and EXO1-defic...

Unraveling cellular longevity pathways in poultry under heat stress: functional…

Shamana(K),Edwin(R),Jaishree(SP),Prashanth(D… In Silico Pharmacol None

...EXO1. The supplementation of Phytocee™ resulted in further increases in these genes, reaching a log2 fold change of 1.32...

Molecular and functional characterization of telomeric repeat-containing RNAs i…

Domingues-Silva(B),Seixas(AF),Azzalin(CM) Nucleic Acids Res 2026-07-17

...EXO1; however, ATM prevents excessive ssDNA accumulation when ARIA function is inhibited. These findings establish CHO c...

DNA damage response genes in lung cancer: Diagnostic, prognostic, and therapeut…

Durán-Toribio(AK),Jiménez-Díaz(IF),Caballé-P… Crit Rev Oncol Hematol 2026-08-15

...EXO1 or RPA polymorphisms are associated with enhanced responsiveness to platinum-based chemotherapy. As well, deleterio...

CTCF primes repressive chromatin for rapid BRCA1/BARD1 recruitment to drive hom…

Hwang(SY),Choi(D),Choi(MJ),Jo(HR),Jeong(JH),… Nucleic Acids Res 2026-07-17

...EXO1/DNA2 is abrogated, which is causally linked to defective DNA end resection and dysfunctional HR. Collectively, our ...

Development and validation of gene expression-based signature for high-grade se…

Vaicekauskaitė(I),Juodakis(J),Kazlauskaitė(P… J Ovarian Res 2026-01-27

...EXO1, RAD50, PPT2, LUC7L2, PKP3, CDCA5, ZFPL1, VPS33B, GRB7, and TCEAL4) was selected for further analysis in the extern...

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