...Exo1-dependent resection of replication forks stalled by Top1-DNA crosslinks. Controlled resection, in turn, allows homo...
...EXO1 is critically important for degradation of uncoupled forks, independent of any degradation at reversed forks. Laggi...
...EXO1, BRCA2, and ESR1 as key hub genes. These genes were upregulated in tumors, showing robust diagnostic performance (A...
...EXO1 and MRE11. Inhibition of MRE11 endonuclease activity with PFM01 suppressed DSB formation after sequential exposure ...
...EXO1-deficient cells. We uncovered differential regulators of cisplatin sensitivity between wildtype (WT) and EXO1-defic...
...EXO1. The supplementation of Phytocee™ resulted in further increases in these genes, reaching a log2 fold change of 1.32...
...EXO1; however, ATM prevents excessive ssDNA accumulation when ARIA function is inhibited. These findings establish CHO c...
...EXO1 or RPA polymorphisms are associated with enhanced responsiveness to platinum-based chemotherapy. As well, deleterio...
...EXO1/DNA2 is abrogated, which is causally linked to defective DNA end resection and dysfunctional HR. Collectively, our ...
...EXO1, RAD50, PPT2, LUC7L2, PKP3, CDCA5, ZFPL1, VPS33B, GRB7, and TCEAL4) was selected for further analysis in the extern...
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