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Genomic profiling in Bulgarian women with ovarian cancer: a dual-sample NGS a...

Kamburova(Z),Popovska(S),Tsvetkov(C) Hered Cancer Clin Pract 2026-03-25

...FANCL and WRN. One patient fulfilled criteria for multi‑locus inherited neoplasia alleles syndrome (MINAS). High‑grade s...

FANCI: from genome guardian to translational therapeutic target.

Zhang(X),Zhang(Y),Chen(M),Wei(J),Li(Y),Dai... Front Oncol None

...FANCL-UBE2T complex, and deubiquitination by USP1-UAF1. This review summarizes the functional mechanisms of FANCI across...

Complement system-related gene signatures implicated in the recurrence of gli...

Sun(Y),Bao(X),Yang(Y),Zhang(P),Tian(N) Transl Cancer Res 2026-06-30

...FANCL, FCER2, TLR2) and constructed a recurrence risk score model. Furthermore, we externally validated the risk score m...

Fancl-mutant mice reveal central role of monoubiquitination in Fanconi anemia...

Liu(L),Glaser(A),Isiaku(AI),Fairfax(K),Cas... Blood Adv 2026-02-10

...FanclTATΔ) that mimics an allele from a patient with FA. This 3-bp deletion removes a catalytic cysteine in the E3 RING ...

Whole Transcriptome Analysis of Male and Female Northern Pike (Esox lucius).

Zhang(J),Wang(Z),Xiao(Q),Fu(X),Li(S),Chen(... Biology (Basel) 2026-06-08

...FANCL, DDX5, SRSF5B) and male-biased genes (STAR, FDX1B, ITGA2B). Furthermore, a competing endogenous RNA (ceRNA) regula...

Real-world clinical outcomes, genetic testing patterns, and treatment pattern...

George(DJ),Kariburyo-Yay(F),Aggarwal(H),Te... Urol Oncol 2026-09-00

...FANCL, PALB2, RAD51B, RAD51C, RAD51D, and RAD54L. Biomarker testing patterns and treatment patterns were reported from i...

Enhanced sensitivity, robust p21 activation, and sustained DNA repair respons...

Kitano(T),Zhu(Z),Minami(N),Orino(K),Yoshik... Front Vet Sci 2025-00-00

...FANCL), a ubiquitin E3 ligase that mediates the monoubiquitylation of FANCD2 as an essential step in the FA pathway. The...

Potential role of Fanconi anemia pathway in the pathogenesis of endometrial c...

Yao(M),Liu(C),Ping(H),Meng(K),Li(X),Li(Q),... Mol Med Rep 2025-11-00

...FANCL, FANCM, FANCN/PALB2, FANCO/RAD51C, FANCP/SLX4, FANCQ/XPF, FANCR/RAD51, FANCS/BRCA1, FANCT/UBE2T, FANCU/XRCC2, FANC...

Piperine Targets the FANCL/UBE2T Complex to Inhibit the FA Pathway and Sensit...

Li(C),Lv(G),Yue(Y),Ma(G),Lu(B) Dose Response 2025-00-00

...FANCL-mediated ubiquitin transfer from UBE2T∼Ub to the ID2 complex, without impairing E2 charging or FANCL-UBE2T binding...

Ginsenoside Rh2 Suppresses the Fanconi Anemia Pathway by Inhibiting NF-κB-Med...

Li(C),Lv(G),Xiong(Z),Wang(Z) Dose Response 2025-00-00

...FANCL expression was analyzed at the transcriptional level, and rescue experiments were performed by FANCL overexpressio...

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