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Lynch Syndrome as a Spectrum of Four Distinct Genetic Disorders: Toward Genotyp…

Liu(Y),Ye(S),Liu(Z),Chen(Z),Liang(X) Cancers (Basel) 2026-02-03

...MSH6, and PMS2). This approach fails to leverage gene-specific characteristics for precision healthcare delivery. This r...

Hereditary Endometrial Cancer: Lynch Syndrome, Mismatch Repair Deficiency, and …

Kluk(A),Gryczka(H),Braszka(M),Ałtyn(R),Marki… Int J Mol Sci 2026-01-28

...MSH6) mutations. Hereditary cancer predisposition typically follows an autosomal dominant inheritance pattern and may be...

Preliminary study of cyto-impedance: Molecular profiling of functional impedanc…

Li(CZ),Zhou(HJ),Chen(JD),Huang(J),Liu(YX),Qi… Biochem Biophys Rep 2026-03-00

...MSH6, RN7SL1, AARS, LCP1, APP, ERLIN2, MIEF1, MEGF8, RPS2, PLK1, ENO1, DOCK8, TNRC18, DCAF7, TPT1, RPL3, CAP1, and PLK4 ...

NOX4-derived oxidative DNA damage impairs thyroid differentiation through an ep…

Radom(M),Buffet(C),Cazarin(J),Harinquet(M),d… Int J Biol Sci None

...MSH6 proteins, which in cooperation with DNMT1, convert these lesions into transcription-blocking events. This mechanism...

Case Report: A case of Lynch syndrome-related glioblastoma with coexisting MSH2…

Huang(L),Tang(X),Cao(D),Li(Y),Zhu(X) Front Oncol None

...MSH6 frameshift mutation synergistically exacerbated genomic instability, highlighting a potential mechanism for LS-driv...

Global Proteomic Analysis of Colorectal Cancers Stratified by Microsatellite In…

Tobias(F),Sekera(ER),Xiong(X),Fang(F),Hampel… bioRxiv 2026-01-29

...MSH6, and PMS2. While the genetic changes associated with Lynch Syndrome have previously been characterized, there have ...

Genomic and immunological differences in endometrial cancer: a comparative stud…

Jiang(S),Li(Y),Wu(S),Wan(J),Li(X) Front Immunol None

...MSH6 alterations. Younger tumors were characterized by activation of stemness and metabolic signaling pathways, whereas ...

Primary peritoneal clear cell carcinoma with metastasis mimicking ovarian carci…

Kim(NI),Lee(JS),Lee(KH),Kim(SS) J Ovarian Res 2026-02-07

...MSH6. Next-generation sequencing revealed ARID1A loss and somatic PIK3CA mutations. No primary ovarian, endometrial, or ...

Artificial intelligence application in routine pathology: ChatGPT-4.0 and Gemin…

Salzano(S),Broggi(G),Zanelli(M),Zizzo(M),Fab… Surg Oncol 2026-04-00

...MSH6 loss (60%) compared to MLH1/PMS2 loss (70%). This drop in sensitivity was attributed to the models' reluctance to c...

Mismatch Repair Deficiency in Benign and Atypical Ocular Sebaceous Neoplasms: I…

Jia(H),Cai(R),Liu(L),Zhang(J),Bi(Y) Am J Ophthalmol 2026-06-00

...MSH6 loss, versus none in sebaceomas (P = .013). Atypical neoplasms also shared other key clinicopathologic features wit...

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