...MSH6, and PMS2). This approach fails to leverage gene-specific characteristics for precision healthcare delivery. This r...
...MSH6) mutations. Hereditary cancer predisposition typically follows an autosomal dominant inheritance pattern and may be...
...MSH6, RN7SL1, AARS, LCP1, APP, ERLIN2, MIEF1, MEGF8, RPS2, PLK1, ENO1, DOCK8, TNRC18, DCAF7, TPT1, RPL3, CAP1, and PLK4 ...
...MSH6 proteins, which in cooperation with DNMT1, convert these lesions into transcription-blocking events. This mechanism...
...MSH6 frameshift mutation synergistically exacerbated genomic instability, highlighting a potential mechanism for LS-driv...
...MSH6, and PMS2. While the genetic changes associated with Lynch Syndrome have previously been characterized, there have ...
...MSH6 alterations. Younger tumors were characterized by activation of stemness and metabolic signaling pathways, whereas ...
...MSH6. Next-generation sequencing revealed ARID1A loss and somatic PIK3CA mutations. No primary ovarian, endometrial, or ...
...MSH6 loss (60%) compared to MLH1/PMS2 loss (70%). This drop in sensitivity was attributed to the models' reluctance to c...
...MSH6 loss, versus none in sebaceomas (P = .013). Atypical neoplasms also shared other key clinicopathologic features wit...
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