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Frequency of bilateral prophylactic and contra-lateral risk-reducing mastecto...

Corso(G),La Vecchia(C),Polizzi(A),Magnoni(... Fam Cancer 2026-04-15

Germline PALB2 variants confer a moderate/high-risk for breast cancer (BC). Recent reports described an increasing atten...

Invasive ductal and lobular carcinoma and receptor status in the genetic cont...

Al-Masri(M),Alayyan(O),Safi(Y) Sci Rep 2026-04-15

...PALB2, and PMS2 are more strongly associated with ILC - to varying degrees. [p < 0.001]. Additionally, ILC tumors kept s...

Evaluating the Impact of ClinGen Variant Curation Expert Panel Criteria Speci...

Marek-Yagel(D),Greenberg(R),Naftali(M),Ben... J Mol Diagn 2026-06-00

...PALB2, whereas LDLR and TPM1 remained largely unchanged. No consistent correlation was found between the extent of crite...

(E)-Labda dial-Loaded Nanoparticles for Triple Negative Breast Cancer.

Munir(A),Rizwan(M),Janbey(A) Curr Drug Targets 2026-04-15

...PALB2, TP53, CHEK2). Lipid-based nanoparticles (LNPs) and polymeric nanoparticles (PNPs) were developed and tested for d...

Results and Exploratory Biomarker Analyses of a Phase II Study CHANGEABLE: Co...

Zhang(J),Du(Y),Meng(Y),Jin(Y),Lin(M),Shao(... MedComm (2020) 2026-04-00

...PALB2 mutations (n = 29) and an exploratory cohort of patients who were either HER2-negative with other DDR mutations, h...

The role of germline mutations in non-small cell lung cancer: A systematic re...

Gentile(G),Gelibter(A),De Marchis(L),Pappa... Crit Rev Oncol Hematol 2026-07-00

...PALB2, CHEK2, and EGFR. Prevalence rates varied by gene, cohort characteristics, ethnicity, and histology with specific ...

Investigating the contribution of rare non-coding variants in BRCA1, BRCA2 an...

Zhao(Q),Li(N),Marinovic(E),McInerny(S),Zet... NPJ Breast Cancer 2026-04-04

Pathogenic coding variants in BRCA1, BRCA2 and PALB2 confer hereditary breast/ovarian cancer risk, yet these regions com...

Comparative Analysis of Homologous Recombination Repair Status Across Gynecol...

Huang(Y),Shao(J),Yin(X),Jiang(Y),Luo(J),Hu... Curr Cancer Drug Targets 2026-04-03

...PALB2 were associated with high HRD scores (≥42). Notably, a subset of patients without germline or somatic mutations in...

Transcriptomic deconvolution reveals prognostic immune signatures and immunot...

Silvestri(V),Valentini(V),Bucalo(A),Porzio... Breast Cancer Res 2026-04-07

...PALB2 (n = 3). Immune characterization included PD-1 and PD-L1 expression, immune scores, and immune cell infiltration u...

Germline Mutation Landscape of Neuroendocrine Tumors in the Chinese Populatio...

Sun(Y),Dong(L),Tan(H),Zhao(D),Zhao(H),Ying... Int J Cancer 2026-08-15

...PALB2, SDHB, and BRIP1. The most common variant of uncertain significance (VUS) was found in MUTYH. Compared with non-ca...

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