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Recruitment of Mre11 to recombination sites during meiosis.

Priyadarshini(P),Survi(M),El Yazidi Mouloud(… Nat Commun 2026-04-07

...Rec114-Mei4 and Mer2, proposed to organize the DSB machinery via biomolecular condensation. Here, we show that Mre11 and...

Genetic Mutations and Non-Genomic Dysregulation in Human Preimplantation Embryo…

Jiang(J),Peng(J),Li(L),Xu(M) Int J Mol Sci 2026-02-25

...REC114, TOP6BL, MEI1, MEI4, TRIP13), spindle assembly (TUBB8 and TUBA4A) and cell cycle and checkpoints (FBXO43, MOS, CH...

A common cause of non-obstructive azoospermia: biallelic MEI1 variants and impl…

Tan(C),Wang(T),Tu(C),Xie(C),Chen(Z),Yuan(S),… J Assist Reprod Genet 2026-04-00

...REC114, MEI4) in co-immunoprecipitation assays. These results not only elucidate its essential function in meiosis and D...

Meiotic gene variants contribute to recurrent blastulation failure.

Chen(X),Leng(L),He(W),Li(W),Li(L),Zhang(X),X… Hum Reprod Open None

...REC114, ANKRD31, DMC1, CNTD1, MLH3, SYCE1, and SYCP2), while three male patients carried MEIKIN variants. Female carrier...

Recruitment of Mre11 to recombination sites during meiosis.

Priyadarshini(P),Survi(M),Yazidi Mouloud(WE)… bioRxiv 2025-07-08

...Rec114-Mei4 and Mer2 (RMM) that organize the meiotic DSB machinery by a mechanism involving biomolecular condensation. H...

Genetic variants in diminished ovarian reserve and premature ovarian insufficie…

Xu(Q),Ding(H),Liu(Y),Han(D),Xia(X),Li(Y),Sha… J Assist Reprod Genet 2025-11-00

...REC114, WRN, BNC1, and HFM1), transcriptional regulation (TBPL2, EIF2B5, and NOBOX), mitochondrial function (TWNK), and ...

Recruitment of Mre11 to recombination sites during meiosis.

Bouuaert(CC),Priyadarshini(P),Survi(M),Moulo… Res Sq 2025-08-19

...Rec114-Mei4 and Mer2 (RMM), which are thought to organize the meiotic DSB machinery by a mechanism involving biomolecula...

Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Ana…

Ma(Li),O'Connell(Jeffrey R),VanRaden(Paul M)… PLoS Genet 2016-06-03

...REC114, were associated with recombination rate in both sexes, whereas three loci, MSH4, SMC3 and CEP55, affected recomb...

ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicat…

Blitzblau(Hannah G),Hochwagen(Andreas) Elife 2015-07-16

...Rec114 and Mre11, and lowered abundance of the Spo11 nuclease. Without this checkpoint, cells formed DSBs on partially r...

Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-…

Carballo(Jesús A),Panizza(Silvia),Serrentino… PLoS Genet 2013-09-10

...Rec114 and DSB hotspot DNA, resulting in a reduction and/or delay in DSB formation. Conversely, a non-phosphorylatable r...

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