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NRZ complex facilitates virus infection via enhancing ER-LD contacts.

Li(Z),Xing(Y),Huang(X),Tian(B),Mei(J),Fu(X),… J Cell Biol 2026-03-02

...RINT1) and zeste white 10 (ZW10), is essential for HCV-induced ER-LD association and viral infection. Mechanistically, R...

Transcriptional and Alternative Splicing Regulation of Autophagy and Vesicle Tr…

Zheng(Z),Chi(H),Liu(X),Chen(X),Pan(Y),Gong(H) Animals (Basel) 2026-04-20

...rint1 (RAD50 interactor 1). Weighted gene co-expression network analysis (WGCNA) of DEGs identified mapk9 (mitogen-activ...

BRIP1-mediated RINT1 acetylation and NF-κB activation promote DNA repair and im…

Wu(H),Zhang(J),Yu(Y),Wang(W),Huang(J),Lin(Z)… Cancer Lett 2026-05-01

...RINT1 at lysine 728, thereby strengthening RINT1-RAD50 interaction, facilitating MRE11-RAD50-NBS1 complex assembly, and ...

Functional analysis of novel and recurrent RINT1 variants in patients with infa…

Aoki(T),Inui(A),Ogata(Y),Igarashi(A),Yanagi(… J Hum Genet 2026-01-00

Rad50-interacting protein (RINT1) interacts with the endoplasmic reticulum (ER) tethering and SNARE complex, playing a c...

Recurrent fever-associated acute liver failure and cranial dysmorphism in child…

Cui(Y),Abudu(F),Simijiang(Y) Front Pediatr 2025-00-00

Mutations in the RINT1 gene represent a rare genetic cause of recurrent fever-associated acute liver failure (ALF) accom...

Unraveling the role of coagulation-related genes in esophageal squamous cell ca…

Deng(L),Fang(C),Zhang(W),Zhu(Z),Gu(Y),Gu(P),… Front Oncol 2025-00-00

...RINT1, and SPTB-in ESCC. A prognostic model based on these genes effectively stratified patients and demonstrated robust...

Recurrent acute liver failure and neutropenia caused by a novel homozygous RINT…

Nuzhnaya(Е),Marakhonov(A),Prokhorov(N),Kan(N… Hum Genomics 2025-10-07

...RINT1, NBAS have been implicated in RALF and are classified as infantile liver failure syndromes type 2 and 3 (ILFS2 and...

Cytokine-Induced Cytotoxicity and Extracellular Matrix Abnormalities in Hepatoc…

Zhang(Y),Ogata(Y),Nadanaka(S),Kitagawa(H),Er… FASEB J 2025-08-15

...RINT1) deficiency has been implicated in recurrent acute liver failure (RALF) triggered by fever or infections. RINT1, t...

Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibi…

Grigaravicius(P),Kaminska(E),Hübner(C A),McK… Cell Death Differ 2016-11-01

...Rint1 in neuroprogenitors led to death at birth. Depletion of Rint1 caused genomic instability due to chromosome fusion ...

BluepRINT for moderate-to-low penetrance cancer susceptibility genes needed: br…

Ngeow(Joanne),Eng(Charis) Cancer Discov 2015-02-24

RINT1 is a novel moderately penetrant cancer susceptibility gene seen in breast cancer as well as possibly in Lynch synd...

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