Shi(M),Gunawan(T),Setzer(M),Okashah(N),Liu... medRxiv 2026-04-20

...RIT2, EXD2, and PPP3CC) were supported by both genomic and proteomic analyses. Druggability assessment highlighted six p...

Zhang(Y),Zhang(Z),Qiu(S),Hu(Y) Front Genet None

...RIT2; and LBD signals near SNCA/MMRN1 and APOE. MAGMA and S-LDSC highlighted amyloid, lipid, immune, synaptic-vesicle an...

Santana-Román(E),Soto-Rojas(LO),Manjarrez(... Neural Regen Res 2026-08-01

...RIT2 + populations, which exhibit subtype-specific transcriptional stress signatures and are preferentially lost in Park...

Mirzaiebadizi(A),Bazgir(F),Mosaddeghzadeh(... Cells 2026-08-28

Both RIT1 and RIT2 are members of the RAS superfamily of small GTPases, which regulate various cellular processes. RIT1 ...

Lu(Yanjun),Liu(Wei),Tan(Kun),Peng(Jing),Zh... Sci Rep 2016-07-25

...RIT2) polymorphism, rs12456492, with Parkinson's disease (PD) are controversial. We performed a meta-analysis to study t...

Chan(Gail),White(Charles C),Winn(Phoebe A)... Neurol Genet 2016-08-09

...RIT2 locus and increased CD33 expression (p joint = 3.50 × 10(-5)) and found strongly suggestive evidence that rs1106018...

Chu(Minjie),Sun(Chongqi),Chen(Weihong),Jin... Toxicol Lett 2015-07-27

...RIT2 and P=2.29×10(-2) for CNTN4). Gene ontology (GO) analyses indicated that the identified variants were significantly...

Liu(Zhen-hua),Guo(Ji-feng),Wang(Ya-qin),Li... Neurobiol Aging 2015-11-24

...RIT2 as a new susceptibility loci. Because the characteristics of this locus in a Han Chinese population from mainland C...

Wang(Jian-Yong),Gong(Mei-Ying),Ye(Yang-Lie... Parkinsonism Relat Disord 2015-11-17

...RIT2 rs12456492 and STX1B rs4889603 as PD susceptible loci. While proteins encoded by the genes, in particular RIT2, may...

Zhang(Xiaona),Niu(Mengyue),Li(Hong),Xie(Anmu) Neurosci Lett 2015-10-28

Many published case-control studies have investigated the association between rs12456492(A/G) variant in RIT2 gene and t...