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Cross-omics interpretable neural network for discovery of molecular markers in …

Chen(X),Yi(S),Yuemaierabola(A),Liu(Y),He(L),… Comput Biol Chem 2026-06-00

...TAF2, which are implicated in prostate cancer progression. These findings are supported by existing literature and provi...

A recently evolved TAF8 isoform arising from an Alu insertion increases TFIID a…

Bernardini(A),Gallo(A),Scheer(E),Morlet(B),D… bioRxiv 2026-01-19

...TAF2, thus giving rise to alternative TFIID sub-complexes in human cells. Our study suggests that the TFIID complex unde...

Integrative Transcriptomic, Network, and Genomic Analysis of Peripheral Blood M…

Krušič(M),Gorenjak(M),Potočnik(U),Marovt(M) Int J Mol Sci 2026-06-05

...TAF2, BUB1B, and RNF135) and genomic variants that may reflect underlying biological mechanisms influencing therapeutic ...

Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID as…

Trowitzsch(Simon),Viola(Cristina),Scheer(Eli… Nat Commun 2016-02-08

...TAF2 binds to multiple motifs within the TAF8 C-terminal region, and these interactions dictate TAF2 incorporation into ...

Structure of promoter-bound TFIID and model of human pre-initiation complex ass…

Louder(Robert K),He(Yuan),López-Blanco(José … Nature 2016-04-20

...TAF2 mediating major interactions with the downstream promoter. TFIIA bridges the TBP-TATA complex with lobe B of TFIID....

Genome-wide pathway analysis of a genome-wide association study on multiple scl…

Song(Gwan Gyu),Choi(Sung Jae),Ji(Jong Dae),L… Mol Biol Rep 2014-03-03

...TAF2], rs669 [A2 M], rs2228043 [IL6ST], rs1061622 [TNFRSF1B], rs1801516 [ATM]) and ten candidate causal pathways, which ...

Microcephaly thin corpus callosum intellectual disability syndrome caused by mu…

Hellman-Aharony(Shlomit),Smirin-Yosef(Pola),… Pediatr Neurol 2014-07-11

...TAF2, which encodes a multisubunit cofactor for TFIID-dependent RNA polymerase II-mediated transcription, in all affecte...

Targeting TBP-Associated Factors in Ovarian Cancer.

Ribeiro(Jennifer R),Lovasco(Lindsay A),Vande… Front Oncol 2014-06-24

...TAF2 exhibits copy number increases or mRNA overexpression in 73% of high-grade serous ovarian cancers (HGSC). At the bi...

Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in…

Parris(T Z),Kovács(A),Hajizadeh(S),Nemes(S),… Oncogenesis 2014-03-25

...TAF2, TATDN1, TRPS1, VPS13B). Taken together, our findings suggest that MYC activity and aberrant DNA methylation may al...

Structural bioinformatics of the general transcription factor TFIID.

Malkowska(Maja),Kokoszynska(Katarzyna),Rychl… Biochimie 2013-08-29

...TAF2 and the high similarity of their putative secondary structures allowed us to model a large part of the TAF2 structu...

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