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TP53 BRCA1 CRISPR single-cell cancer

Aggarwal(Anita),Liu(Min-Ling),Krasnow(Stev... J Community Support Oncol 2016-07-02

...BRCA2-positve. ER/PR (estrogen-/progesterone-receptor) was positive in 71%, ER-positive/PR-negative in 2%, ER-positive/P...

Govatati(Suresh),Challa(Kiran),Reddy(Sunit... J Assist Reprod Genet 2016-04-28

To investigate the role of genetic variations and expression alterations of BRCA1 and BRCA2 genes in the pathophysiology...

Abdollahian(Mehrnaz),Das(Tapas K) IEEE J Biomed Health Inform 2016-01-05

...BRCA2 mutation carriers at age 30, the cost-optimal strategy is PO at age 30, PM at age 40, and yearly screening only af...

Garre(P),Martín(L),Sanz(J),Romero(A),Tosar... Clin Genet 2016-02-02

...BRCA2 in 48 FCCX probands. We identified 29 variants including a frameshift mutation. Deleterious variant c.3847_3848del...

Singer(C F),Rappaport-Fuerhauser(C),Sopik(... Clin Genet 2016-04-25

Men with a BRCA2 mutation face substantial lifetime risks for the development of both breast and prostate cancer. A male...

Guo(Huan),Bassig(Bryan A),Lan(Qing),Zhu(Yo... Cancer Causes Control 2016-01-11

...BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70...

Sopik(V),Phelan(C),Cybulski(C),Narod(S A) Clin Genet 2016-01-04

Women who carry a BRCA1 or BRCA2 mutation are at high risk of breast and ovarian cancer, and may be at moderately increa...

van den Broek(Alexandra J),de Ruiter(Karen... Eur J Hum Genet 2016-01-06

...BRCA2 mutation carriers identified met the criteria for referral to the CGC based on age, family history and synchronous...

Ray(Debra),Grumet(Sherry),Lagmay-Fuentes(P... J Community Support Oncol 2016-07-02

...BRCA2 mutation (Myriad, Tyrer-Cuzick, BRCAPRO) and lifetime risk of breast cancer (Gail, Claus, Tyrer-Cuzick, BRCAPRO) u...

Trottier(M),Lunn(J),Butler(R),Curling(D),T... Clin Genet 2016-04-25

...BRCA2 mutations among unselected breast cancer patients in the Bahamas is 23%. It is beneficial to advise relatives of m...

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