Considering the importance of BRCA1, BRCA2, CHEK2 and TP53 in the development of hereditary early-onset breast and ovari...
...BRCA2 and TP53 mutation screening, respectively, and 7 for CHEK2 1100delC testing. A deleterious BRCA2 mutation was iden...
...BRCA2 genetic testing, for this group of patients, especially in the South and Southeast of Brazil.
...BRCA2 are responsible for most of the known causes of HBOC, while mutations in mismatch repair genes and several genes o...
Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. Alt...
...BRCA2 are found in only a minority of breast cancer patients, their impact for those patients is important. It is a powe...
...BRCA2. These new findings indicate an important backup role for Rad52, which complements the main HR mechanism in mammal...
...BRCA2's 3'UTR. Our results suggest that BRCA2 is subject to a complex post-transcriptional regulatory program that has s...
...BRCA2 genes or in mismatch repair (MMR) genes, such as MLH1 and MSH2. Women harboring deleterious mutations in these gen...
The genotype-phenotype correlations of the specific BRCA1 and BRCA2 mutations in multi-ethnic populations in USA have no...
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