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TP53 BRCA1 CRISPR single-cell cancer

Laitman(Yael),Keinan Boker(Lital),Liphsitz... Breast Cancer Res Treat 2016-01-01

...BRCA2 mutation carriers are still unsettled. Cancer risks in men who were found to harbor a BRCA1 (n = 150) or a BRCA2 (...

De Felice(Francesca),Marchetti(Claudia),Mu... Ann Surg Oncol 2016-05-12

Women with BRCA1 and BRCA2 mutations have substantially elevated risk of developing breast cancer. The aim of this study...

Snyder(C),Metcalfe(K),Sopik(V),Royer(R),Zh... Breast Cancer Res Treat 2016-01-01

...BRCA2. Two of 90 breast cancer patients (2.2 %) were found to carry a truncating mutation in PALB2 (c.2411_2412delCT and...

Kusch(Thomas) J Cell Sci 2016-03-29

...Brca2 associates with lamin and the cohesion factor Pds5 to secure persistent recombination sites at the nuclear envelop...

Shiovitz(S),Korde(L A) Ann Oncol 2016-04-05

...BRCA2, PTEN, TP53, CDH1, and STK11), which confer up to an 80% lifetime risk of breast cancer. An additional 2%-3% of ca...

Singer(C F),Rappaport-Fuerhauser(C),Sopik(... Clin Genet 2016-04-25

Men with a BRCA2 mutation face substantial lifetime risks for the development of both breast and prostate cancer. A male...

Trottier(M),Lunn(J),Butler(R),Curling(D),T... Clin Genet 2016-04-25

...BRCA2 mutations among unselected breast cancer patients in the Bahamas is 23%. It is beneficial to advise relatives of m...

Andersen(M Robyn),Thorpe(Jason),Buist(Dian... Behav Med 2016-10-19

...BRCA2 are at substantially elevated risk for ovarian cancer. To understand what percentage of women with high-risk famil...

Sopik(V),Phelan(C),Cybulski(C),Narod(S A) Clin Genet 2016-01-04

Women who carry a BRCA1 or BRCA2 mutation are at high risk of breast and ovarian cancer, and may be at moderately increa...

Guo(Huan),Bassig(Bryan A),Lan(Qing),Zhu(Yo... Cancer Causes Control 2016-01-11

...BRCA2 rs144848 AC+CC [odds ratio (OR) (95% confidence interval (CI)) 3.28(1.27-8.50)], WRN rs1346044 TT [OR(95% CI) 2.70...

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