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TP53 BRCA1 CRISPR single-cell cancer

Pranatharthi(Annapurna),Ross(Cecil),Srivas... Stem Cells Int 2016-09-06

...BRCA2 in the regulation of cell division. Incidentally, statins (drug for cardiovascular ailment) are functional inhibit...

Kang(Hyunseok P),Maguire(Jared R),Chu(Clem... PeerJ 2016-07-04

Hereditary breast and ovarian cancer syndrome, caused by a germline pathogenic variant in the BRCA1 or BRCA2 (BRCA1/2) g...

Maeshima(Yurina),Oseto(Kumiko),Katsuragi(R... J Breast Cancer 2016-07-06

...BRCA2 mutation carrier. She underwent prophylactic bilateral skin-sparing mastectomy (SSM) with excision of the nipple a...

Pritchard(Colin C),Mateo(Joaquin),Walsh(Mi... N Engl J Med 2016-08-18

Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. Alt...

Lopez(Veronica Aedo),Stravodimou(Athina),U... Rev Med Suisse 2016-07-26

...BRCA2 are found in only a minority of breast cancer patients, their impact for those patients is important. It is a powe...

Rashid(Muhammad U),Naeemi(Humaira),Muhamma... Hered Cancer Clin Pract 2016-07-14

...BRCA2 genes or in mismatch repair (MMR) genes, such as MLH1 and MSH2. Women harboring deleterious mutations in these gen...

Yılmaz(Nafiye Karakaş),Karagin(Peren Hatic... J Turk Ger Gynecol Assoc 2016-07-12

...BRCA2 gene mutation. Therefore, in the present study, we aimed to investigate the role of BRCA1 and BRCA2 gene mutations...

Hanamshet(Kritika),Mazina(Olga M),Mazin(Al... Genes (Basel) 2016-09-21

...BRCA2. These new findings indicate an important backup role for Rad52, which complements the main HR mechanism in mammal...

Mogilyansky(Elena),Clark(Peter),Quann(Kevi... Front Genet 2016-09-16

...BRCA2's 3'UTR. Our results suggest that BRCA2 is subject to a complex post-transcriptional regulatory program that has s...

Palmbos(Phillip L),Hussain(Maha H) Oncology (Williston Park) 2016-07-01

...BRCA2, or ATM. Emerging data suggest that drugs that target poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) e...

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