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Durable Clinical Benefit of Pertuzumab in a Young Patient with BRCA2 Mutation...

Koumarianou(Anna),Kontopoulou(Christina),K... Case Rep Oncol Med 2016-05-19

...BRCA2 mutations are reported to be rarely associated with HER2-overexpressing advanced breast cancer and even more rarel...

Current and emerging breast cancer biomarkers.

Sana(Maryam),Malik(Hassan Jameel) J Cancer Res Ther 2016-08-26

...BRCA2, p53, HER2-neu, cyclin D1, and cyclin E, which are briefly described in this review.

Comprehensive genomic profiling of inflammatory breast cancer cases reveals a...

Ross(Jeffrey S),Ali(Siraj M),Wang(Kai),Kha... Breast Cancer Res Treat 2016-08-08

...BRCA2 (15 %), and PTEN (15 %). In the TNBC subset of IBC, 8/19 (42 %) showed MYC amplification (median copy number 8X, r...

Common cancer-associated imbalances in the DNA damage response confer sensiti...

Middleton(Fiona K),Patterson(Miranda J),El... Oncotarget 2016-08-12

...BRCA2 and XRCC3) and base excision repair (BER: XRCC1) conferred sensitivity to VE-821. Surprisingly, the loss of differ...

Risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 3...

Basu(N N),Ingham(S),Hodson(J),Lalloo(F),Bu... Fam Cancer 2016-08-26

BRCA1 and BRCA2 mutation carriers have an increased risk of contralateral breast cancer after primary breast cancer. Ris...

Variation in breast cancer risk associated with factors related to pregnancie...

Lecarpentier(Julie),Noguès(Catherine),Mour... Breast Cancer Res 2015-06-24

...BRCA2 mutation carriers and could also be helpful in understanding how BRCA1 and BRCA2 genes are involved in BC.

Promoter hypermethylation in male breast cancer: analysis by multiplex ligati...

Kornegoor(Robert),Moelans(Cathy B),Verschu... Breast Cancer Res 2015-06-24

...BRCA2 (P < 0.001). The most frequently hypermethylated genes (MSH6, CDH13, PAX5, PAX6 and WT1) were similar for male and...

Platinum chemotherapy for BRCA1-related breast cancer: do we need more evidence?

Turner(Nicholas C),Tutt(Andrew N J) Breast Cancer Res 2015-06-25

...BRCA2-related breast cancer is discussed.

Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) los...

Phuah(Sze-Yee),Looi(Lai-Meng),Hassan(Norha... Breast Cancer Res 2015-01-14

...BRCA2 were analyzed by Sanger sequencing and multiple ligation-dependent probe amplification (MLPA) analysis in 431 wome...

[Interest in breast cancer genetic testing among Icelandic women.].

Arnadóttir(G),Sigurðardóttir(V),Jónsson(F ... Laeknabladid 2015-10-26

...BRCA2). Before genetic testing becomes widely available in Iceland it is important to understand what motivates women s ...

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