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TP53 BRCA1 CRISPR single-cell cancer

Guaragnella(Nicoletta),Palermo(Vanessa),Ga... FEMS Yeast Res 2015-08-07

...BRCA2, which are among the best-known cancer-susceptibility genes, with the aim of understanding their role in tumorigen...

Finch(A),Bacopulos(S),Rosen(B),Fan(I),Brad... Clin Genet 2015-06-18

Genetic testing for BRCA1 and BRCA2 gene mutations, in conjunction with preventive salpingo-oophorectomy for mutation ca...

Rhiem(Kerstin),Engel(Christoph),Graeser(Mo... Breast Cancer Res 2015-01-14

While it has been reported that the risk of contralateral breast cancer in patients from BRCA1 or BRCA2 positive familie...

Wang(Wei),Li(Jia-Lin),He(Xiao-Feng),Li(An-... PLoS One 2015-02-04

...BRCA2 mutation carriers (recessive model: OR = 4.88, 95% CI = 1.10-21.67; additive model: OR = 4.92, 95% CI = 1.11-21.83...

Phuah(Sze Yee),Lee(Sheau Yee),Kang(Peter),... PLoS One 2015-01-15

The partner and localizer of breast cancer 2 (PALB2) is responsible for facilitating BRCA2-mediated DNA repair by servin...

Maxwell(Kara N),Nathanson(Katherine L) Breast Cancer Res 2015-05-18

...BRCA2 and TP53 lead to autosomal dominant inherited cancer susceptibility and confer a high lifetime risk of breast canc...

Riahi(A),Kharrat(M),Ghourabi(M E),Khomsi(F... Clin Genet 2015-09-16

The contribution of BRCA1/BRCA2 mutations to hereditary breast cancer in the Tunisian population has not been accurately...

Van Allen(E M),Foye(A),Wagle(N),Kim(W),Car... Prostate Cancer Prostatic D... 2015-01-23

...BRCA2 gene.,We demonstrate the feasibility of diagnostic bone metastases profiling and analysis that will be required fo...

Chen(Ying),Bancroft(Elizabeth),Ashley(Sue)... Fam Cancer 2015-02-07

...BRCA2 carriers had RRBSO, with a further 26 BRCA1 carriers, 28 BRCA2 carriers and one non-carrier developing ovarian can...

Bakker(Janine L),Thirthagiri(Eswary),van M... Hum Mutat 2015-01-29

...BRCA2 (FANCD1) is one of the 16 genes involved in this recessive disease. We have identified a novel mutation of the spl...

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