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TP53 BRCA1 CRISPR single-cell cancer

Szabova(Ludmila),Bupp(Sujata),Kamal(Muhaym... PLoS One 2015-05-29

...Brca2 that develop serous epithelial ovarian cancer (SEOC) closely resembling the human disease on histologic and molecu...

Aparicio(Tomas),Baer(Richard),Gautier(Jean... DNA Repair (Amst) 2015-02-12

...BRCA2 mutations, that disrupt DSB repair are often associated with cancer susceptibility. In addition, recent evidence s...

Diergaarde(Brenda),Kurta(Michelle L) Curr Opin Obstet Gynecol 2015-01-12

...BRCA2 mutations and borderline ovarian tumours, still remain. In addition, it may currently just be too early to determi...

Chong(Hansook Kim),Wang(Tao),Lu(Hsiao-Mei)... PLoS One 2015-01-29

...BRCA2 account for a high percentage of hereditary cases, there are more than 25 susceptibility genes that differentially...

Yata(Keiko),Bleuyard(Jean-Yves),Nakato(Ryu... Cell Rep 2015-08-21

...BRCA2, a key Rad51 binding partner, coordinates the activity of the central cell-cycle drivers CDKs and Plk1 to promote ...

Wheler(Jennifer J),Parker(Barbara A),Lee(J... Oncotarget 2015-02-19

...BRCA2, EGFR, IRS2, CDH1, CDKN2A, FGF19, FGF3 and FGF4. Aberrations included mutations (46%), amplifications (45%), delet...

Doss(C George Priya),Nagasundaram(N) Cell Biochem Biophys 2015-07-02

...BRCA2-PALB2, and F1524V, V1532F in FANCD1/BRCA2-RAD51). Analysis of the MD trajectories indicated that predicted deleter...

Sharma(Priyanka),Klemp(Jennifer R),Kimler(... Breast Cancer Res Treat 2015-01-12

...BRCA2:4.3 %). SFH reported by 36 % of patients. Mutation prevalence in patients with and without SFH was 31.6 and 6.1 %,...

LaDuca(Holly),Stuenkel(A J),Dolinsky(Jill ... Genet Med 2015-07-06

...BRCA2 not included), depending on the panel ordered (BreastNext, OvaNext, ColoNext, or CancerNext). Next-generation sequ...

Mastoraki(Aikaterini),Chatzimavridou-Grigo... J Gastrointest Cancer 2015-03-31

...BRCA2, and hereditary nonpolyposis colorectal cancer (HNPCC) mutation carriers. It was also agreed that initial screenin...

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