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Altered significance of D'Amico risk classification in patients with prostate...

Bolton(Damien),Cheng(Yuan),Willems-Jones(A... BJU Int 2015-10-16

...BRCA2 mutation was undertaken in each instance. Prostate cancers were analysed by BRCA2 carrier vs non-carrier status fo...

Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resi...

Maleki Vareki(Saman),Rytelewski(Mateusz),F... Oncotarget 2015-02-19

...BRCA2 sensitizes human lung cancer cells to olaparib and cisplatin. Antisense reduction of IDO decreased NAD+ in human t...

The negative interplay between Aurora A/B and BRCA1/2 controls cancer cell gr...

Wang(Yan),Wang(Ziliang),Qi(Zihao),Yin(Shen... Mol Cancer 2015-01-12

...BRCA2-deficient pancreatic cancer cell line Capan-1 and in ovarian cancer cell line OVCA433, Aur A/B and BRCA1/2 inverse...

KIF14 promotes AKT phosphorylation and contributes to chemoresistance in trip...

Singel(Stina M),Cornelius(Crystal),Zaganjo... Neoplasia 2015-05-12

...BRCA2 mutation carriers showed increased KIF14 mRNA expression by fluorescence in situ hybridization compared to control...

Assessment of individuals with BRCA1 and BRCA2 large rearrangements in high-r...

Arnold(Angela G),Otegbeye(Ebunoluwa),Fleis... Breast Cancer Res Treat 2015-01-12

...BRCA2. Seventeen unrelated probands carried a private BRCA1/2 LR (17/150, 11.3 % of all detectable non-AJ mutations). At...

Risk factors for ovarian cancers with and without microsatellite instability.

Segev(Yakir),Pal(Tuya),Rosen(Barry),McLaug... Int J Gynecol Cancer 2015-02-13

...BRCA2 mutation status, past oral contraceptive use, and tubal ligation. Similarly, we compared the distribution of the h...

New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed b...

Ross(Jeffrey S),Wang(Kai),Gay(Laurie),Al-R... Oncologist 2015-01-12

...BRCA2 (4%), NF1 (4%), PIK3CA (4%), PTCH1 (4%), and TSC1 (4%). Four (14%) of the ICC cases featured novel gene fusions in...

BRCA1/2 germline mutations and their clinical importance in Turkish breast ca...

Cecener(Gulsah),Egeli(Unal),Tunca(Berrin),... Cancer Invest 2015-01-06

...BRCA2;V2466A) related with disease. Our findings contribute significantly to the types of germline BRCA1/BRCA2 mutations...

Tissue-specific effects of valproic acid on DNA repair genes and apoptosis in...

Lamparter(Christina),Winn(Louise M) Toxicol Sci 2015-10-23

...Brca2, with Western blotting used to quantify Rad51, cleaved caspase-3 and cleaved-PARP protein. Increased recombination...

MicroRNA expression signatures for the prediction of BRCA1/2 mutation-associa...

Tanic(Miljana),Yanowski(Kira),Gómez-López(... Int J Cancer 2015-01-23

...BRCA2 is indicated for patients with breast cancer from high-risk breast cancer families and influences both treatment o...

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