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Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict b...

Vollebergh(Marieke A),Lips(Esther H),Neder... Breast Cancer Res 2015-04-16

...BRCA2-mutated breast cancers can identify breast cancer patients with TN as well as ER-positive, HER2-negative tumors th...

Applications for breast magnetic resonance imaging.

Pilewskie(Melissa),Morrow(Monica) Surg Oncol Clin N Am 2015-02-12

...BRCA2 mutations, a family history suggesting a hereditary breast cancer syndrome, or a history of chest wall radiation.

VEGFR3 inhibition chemosensitizes ovarian cancer stemlike cells through down-...

Lim(Jaeyoung J),Yang(Kun),Taylor-Harding(B... Neoplasia 2015-01-23

...BRCA2. Inhibition of VEGFR3 in ovarian tumor cells was associated with growth arrest. CD133(+) ovarian cancer stemlike c...

Breast cancer: major risk factors and recent developments in treatment.

Majeed(Wafa),Aslam(Bilal),Javed(Ijaz),Khal... Asian Pac J Cancer Prev 2015-01-06

...BRCA2 genes. Obesity, hormone therapy and use of alcohol are possible causes and over-expression of leptin in adipose ti...

Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familia...

De Silva(Sumadee),Tennekoon(Kamani Hemamal... BMC Res Notes 2015-01-20

...BRCA2 rearrangement was also identified in the cohort.,Thus this study demonstrates that BRCA1 and BRCA2 large genomic r...

Silencing of BRCA2 decreases anoikis and its heterologous expression sensitiz...

Guaragnella(Nicoletta),Marra(Ersilia),Gall... Apoptosis 2015-03-30

...BRCA2 in the regulation of anoikis has not been investigated. Here, we found that suppression of BRCA2 expression by sho...

Genetic testing and familial implications in breast-ovarian cancer families.

Oosterwijk(Jan C),de Vries(Jakob),Mourits(... Maturitas 2015-03-30

...BRCA2 has become incorporated in the diagnostic procedure of patients with breast and/or ovarian cancer. Since 1994 an i...

A multi-institutional study on the association between BRCA1/BRCA2 mutational...

Seong(Moon-Woo),Kim(Kyu Hyung),Chung(Il Yo... Breast Cancer Res Treat 2015-08-18

...BRCA2 mutations: 49.4 versus 50.6 %, respectively. TNBC was diagnosed in 35.2 % of BRCA1/2 mutation carriers and 57.1 % ...

Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN c...

Damiola(Francesca),Pertesi(Maroulio),Olive... Breast Cancer Res 2015-04-16

...BRCA2, and CHEK2, and then assessed by logistic regression.,Re-analysis of our ATM, BRCA1, and BRCA2 mutation screening ...

BRCA2 promoter polymorphism is associated with breast cancer prognosis in Chi...

Liu(Lu),Fang(Yi),Fan(Jianlin),Hu(Jianming)... Chin Med J (Engl) 2015-04-06

...BRCA2) is an important breast cancer-susceptibility gene. Promoter polymorphisms in BRCA2 may affect its transcription a...

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