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Germline genetic profiling utilizing multigene panel testing in Jordanian pat...

Abdel-Razeq(H),Saleh(Y),Hani(HB),Abdel-Raz... BMC Cancer 2026-02-10

...BRCA2 (n = 8), while 8 others (3.8%) had increased risk allele in APC. Other variants identified included ATM, CFTR, CHE...

Syndrome of Inappropriate Antidiuretic Hormone Secretion and Thrombotic Micro...

Shapoo(N),Izaguirre(C),Rehman(A),Mattana(J... Cureus 2026-01-00

Metastatic prostate cancer with a BRCA2 mutation is associated with aggressive clinical behavior and poor outcomes with ...

Concurrent Germline-Somatic Alterations and Associations with Cancer Outcomes...

Pal(LR),Schäffer(AA),Avila(S),Wooten(J),Bu... Res Sq 2026-02-02

...BRCA2/somatic TP53 and germline BRCA1/somatic TP53 (n=40 and n=38 studies, respectively). Statistical testing was perfor...

Single-Electrode High-Throughput 12-Well Array Electrochemiluminescence Imagi...

Dong(Y),Fu(B),Wu(H),Jie(G) Anal Chem 2026-02-24

...BRCA2). Two newly explored luminophores, the Eu-luminol complex and Ru/Zn MOF with blue and orange-red high-intensity EC...

Prostate cancer germline variants with therapeutic implications.

Bitaraf(M),Castro(E),Sharifi(N) Trends Mol Med 2026-05-00

...BRCA2, and HSD3B1 are the most prevalent alterations in men with advanced prostate cancer and are associated with increa...

Overcoming Resistance to PARP Inhibitors in BRCA-Mutated Cancers: Mechanisms ...

Guo(J),Wang(Y),Li(J),Jiang(Z) J Cancer 2026-00-00

...BRCA2 are essential for homologous recombination (HR) repair. Mutations in BRCA1/2 compromise HR repair efficacy, result...

Clinicopathologic Spectrum and Intraprostatic Heterogeneity of Primary Mismat...

Martin(D),Cheung(CC),Yang(C),Beauchamp(L),... Am J Surg Pathol 2026-09-15

...BRCA2. Germline testing performed in 15 cases identified Lynch syndrome in 5 (33%). MMR immunohistochemistry performed o...

Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical ...

Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),... Cancers (Basel) 2026-08-29

...BRCA2 were identified in 19 cases (11.51%), including 8 in BRCA1 and 11 in BRCA2. The presence of BRCA P/LPVs associated...

Development and Real-World Evaluation of a Statewide Mainstream Model of Germ...

Jennings(CA),Cornthwaite(K),Osborn(M),Kich... Asia Pac J Clin Oncol 2026-02-00

...BRCA2 and mismatch repair (MMR) genes across South Australia. Participatory action research (PAR) and implementation sci...

Decoding the Transcriptional Complexity of the Human BRCA2 DNA Repair Gene Us...

Adamopoulos(PG),Boti(MA),Athanasopoulou(K)... Biochem Genet 2026-06-00

...BRCA2 sv.7-sv.56), expanding the known transcript repertoire of BRCA2 gene. Notably, transcript variants sv.9, sv.15, an...

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