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Predicting the Pathogenic Potential of BRCA1 and BRCA2 Gene Variants Identifi...

Brookes(Clare),Lai(Stella),Doherty(Elaine)... Sultan Qaboos Univ Med J 2015-06-08

...BRCA2 genes. Pathogenic mutations in the BRCA1 and BRCA2 genes lead to an increased risk of developing breast, ovarian, ...

[Risky factors in ovarian cancer (our and foreign experience)].

Ivanov(S) Akush Ginekol (Sofiia) 2015-08-27

...BRCA2 gene mutations. The patients who want to preserve their reproductive functions orto postpone the preventive surger...

Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in th...

Miele(Evelina),Mastronuzzi(Angela),Po(Agne... Biomark Res 2015-06-11

...BRCA2/FANCD1 or its associated gene PALB2/FANCN. We report the case of a patient affected by Fanconi Anemia with Wilms t...

A Comparative Analysis of Breast and Ovarian Cancer-related Gene Mutations in...

Amemiya(Yutaka),Bacopulos(Stephanie),Al-Sh... Anticancer Res 2015-08-06

...BRCA2 as well as 21 additional genes, including, ATM, BARD1, CDH1, P53, EPCAM, MSH6, and RAD50, which have been implicat...

[Ethnic aspects of hereditary breast cancer in the region of Siberia].

Cherdyntseva(N V),Pisareva(L F),Ivanova(A ... Vestn Ross Akad Med Nauk 2015-06-12

...BRCA2 6174delT) in women diagnosed with breast cancer among indigenous people and newcomers living in Siberia.,We tested...

Association between RAD51 polymorphism and breast cancer susceptibility: a me...

Li(Wei),Liu(Ke-Jia),Song(Jing-Song),Song(R... Int J Clin Exp Med 2015-05-01

...BRCA2 could modulate the penetrance of BRCA1/BRCA2 mutations, which may increase susceptibility for breast cancer by inh...

Associations of common breast cancer susceptibility alleles with risk of brea...

Kuchenbaecker(Karoline B),Neuhausen(Susan ... Breast Cancer Res 2015-11-09

...BRCA2 carriers.,We used data from 15,252 BRCA1 and 8,211 BRCA2 carriers to analyze the associations between approximatel...

Pan-cancer analysis of genomic scar signatures associated with homologous rec...

Marquard(Andrea M),Eklund(Aron C),Joshi(Te... Biomark Res 2015-05-27

Ovarian and triple-negative breast cancers with BRCA1 or BRCA2 loss are highly sensitive to treatment with PARP inhibito...

Epidemiological and clinicopathological characteristics of BRCA-positive and ...

Triantafyllidou(Olga),Vlachos(Ioannis S),A... J BUON 2015-11-12

...BRCA2. Collected data included demographics, pedigrees, tumor histopathology and immunohistochemistry findings.,In BRCA1...

Multigene panel analysis identified germline mutations of DNA repair genes in...

Hirotsu(Yosuke),Nakagomi(Hiroshi),Sakamoto... Mol Genet Genomic Med 2015-10-05

...BRCA2 tumor suppressor genes account for a high penetrance of hereditary cases, but familial cases without mutations in ...

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