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Clinical and pathological characteristics of Hispanic BRCA-associated breast ...

Nahleh(Zeina),Otoukesh(Salman),Dwivedi(Alo... Am J Cancer Res 2015-01-28

...BRCA2 mutations. A total of 17 deleterious BRCA Mutations were observed. Seven have been previously reported as specific...

Identification of a new BRCA2 large genomic deletion associated with high ris...

Timoteo(Ana Rafaela de Souza),Albuquerque(... Hered Cancer Clin Pract 2015-01-29

...BRCA2 germline mutation that is a large genomic deletion of 3,492 nucleotides including BRCA2 exon 14, and this deletion...

Women In Steady Exercise Research (WISER) Sister: study design and methods.

Schmitz(Kathryn H),Williams(Nancy I),Konto... Contemp Clin Trials 2015-12-29

...BRCA2 mutation and/or ≥ 18% lifetime risk according to prediction models). A 1:1:1 randomization scheme was used to allo...

The future of breast cancer systemic therapy: the next 10 years.

Telli(Melinda L),Sledge(George W) J Mol Med (Berl) 2015-09-24

...BRCA2 mutations, which may be responsible for breast cancer carcinogenesis and, importantly, may have implications for t...

Tumor-associated mutations in a conserved structural motif alter physical and...

Chen(Jianhong),Morrical(Milagros D),Doniga... Nucleic Acids Res 2015-05-01

...BRCA2 and other proteins that control RAD51 activity are associated with human cancer. Here we describe a set of mutatio...

Tumor-associated inflammation as a potential prognostic tool in BRCA1/2-assoc...

van Verschuer(Victorien M T),Hooning(Maart... Hum Pathol 2015-03-20

...BRCA2 breast cancer patients. Median follow-up after diagnosis was 9.7 years. Independent prognostic factors for RFS wer...

Candidate gene analysis of BRCA1/2 mutation-negative high-risk Russian breast...

Sokolenko(Anna P),Preobrazhenskaya(Elena V... Cancer Lett 2015-04-20

...BRCA2 entire coding region as well as for founder disease-predisposing alleles in CHEK2, NBN/NBS1 and ATM genes. Full-le...

Hereditary predisposition to ovarian cancer, looking beyond BRCA1/BRCA2.

Minion(Lindsey E),Dolinsky(Jill S),Chase(D... Gynecol Oncol 2015-05-28

...BRCA2 negative population of patients with a personal history of breast and/or ovarian cancer by means of a hereditary c...

[Significance and expressions of BRCA1 and BRCA2 protein in sporadic breast c...

Ma(Jinzhu),Liu(Ming) Zhonghua Yi Xue Za Zhi 2015-09-08

...BRCA2 protein in breast cancer tissues (r = 0.673, P > 0.05).,The aberrant expressions of BRCA1 and BRCA2 protein plays ...

Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Pr...

Park(See-Hyoung),Noh(Sang Jae),Kim(Kyoung ... Transl Oncol 2015-08-28

Poly(ADP-ribose) polymerase 1 (PARP1), γH2AX, BRCA1, and BRCA2 are conventional molecular indicators of DNA damage in ce...

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