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Zhu(Y),Wang(Y),Shen(Z),Shen(L),Liu(H),Xian... Chin Med J (Engl) 2026-06-20

...BRCA2 RAD51-binding domain (RAD51-BD) mutations (HR, 0.29; 95% CI, 0.11-0.79; P = 0.010). BRCA1 BRCT1 mutations are asso...

Habib(R),Arnold(E),Obi(T),Vizeacoumar(FJ),... Curr Oncol 2026-07-28

...BRCA2 pathogenic variants, immune checkpoint inhibition for mismatch repair-deficient or microsatellite instability-high...

Wong(SM),Blondeaux(E),Delucchi(V),Coussy(F... JAMA Netw Open 2026-08-03

...BRCA2 (BRCA1/2) carriers diagnosed with early-onset breast cancer. The BRCA BCY Collaboration is an international, hospi...

Arduini(A),Polati(R),Bonisoli(GL),Sina(S) Reports (MDPI) 2026-08-05

...BRCA2 is limited. Hence, we present a rare case of a 51-year-old patient with a germline BRCA2 pathogenic variant affect...

Shin(JE),Lee(E),Ha(SY),Lim(SH),Cho(YB),Par... JCO Precis Oncol 2026-08-00

...BRCA2, BARD1, FAT1, HIST1H1C, and LRP1B, whereas canonical drivers showed no significant age-dependent trends. In metast...

Galego-Carro(J),Santamariña(M),Blanco-Pére... Eur Urol Open Sci 2026-09-00

...BRCA2 variants were significantly enriched in patients compared with non-cancer control cohorts. BRCA1/BRCA2 carriers ha...

McKenzie(J),Howard(L),Park(JJ),Ashraf(B),S... Prostate Cancer Prostatic D... 2026-08-05

...BRCA2 (HR 2.12 [95%CI 1.02-4.42], p = 0.045) additionally associated with PFS, and RAD21 (HR 2.55 [95%CI 1.13-5.77], p =...

Shatalov(PA),Bukaeva(AA),Veselovsky(EM),Tr... Biomedicines 2026-08-01

...BRCA2 (48 vs. 5 carriers) and the recurrent BRCA1 c.5329dup variant accounting for 23 cases. In the exome subset, 79 of ...

Milambo(JPM),Chitha(WW) Asian Pac J Cancer Prev 2026-08-01

BRCA1 and BRCA2 gene mutations are major contributors to hereditary breast and ovarian cancer syndrome (HBOC). While mut...

Sukpan(P),Khongcharoen(N),Samphao(S) Asian Pac J Cancer Prev 2026-08-01

...BRCA2 genes. This study represents the first and largest investigation of germline CNVs in the BRCA1 and BRCA2 genes wit...