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Cancel all Hollidays for SLX4 mutations: identification of a new Fanconi anemia…

Kang(M H) Clin Genet 2011-09-28

SLX4, a coordinator of structure-specific endo-nucleases, is mutated in a new Fanconi anemia subtype Stoepker et al. (20...

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fancon…

Yamamoto(Kimiyo N),Kobayashi(Shunsuke),Tsuda… Proc Natl Acad Sci U S A 2011-06-17

...SLX4 more closely, we disrupted the SLX4 gene in avian DT40 cells. SLX4 deficiency caused cell death associated with ext...

Aberrant chromosome morphology in human cells defective for Holliday junction r…

Wechsler(Thomas),Newman(Scott),West(Stephen … Nature 2011-05-25

...SLX4 reduces the high frequency of SCEs in Bloom's syndrome cells, indicating that MUS81 and SLX4 promote SCE formation,...

Mutations of the SLX4 gene in Fanconi anemia.

Kim(Yonghwan),Lach(Francis P),Desetty(Rohini… Nat Genet 2011-03-31

...SLX4, demonstrating that biallelic mutations in SLX4 (renamed here as FANCP) cause a new subtype of Fanconi anemia, Fanc...

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocop…

Crossan(Gerry P),van der Weyden(Louise),Rosa… Nat Genet 2011-03-31

...SLX4 protein, a key regulator of nucleases, is critical for DNA damage response. SLX4 nuclease complexes mediate repair ...

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fa…

Stoepker(Chantal),Hain(Karolina),Schuster(Be… Nat Genet 2011-03-31

...SLX4. These individuals, who were previously diagnosed as having Fanconi anemia, add SLX4 as an essential component to t...

Hpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease…

Sokolowska(Monika),Czapinska(Honorata),Bocht… Nucleic Acids Res 2011-05-12

...Slx4, the prokaryotic nucleotide excision repair proteins UvrC and Cho, and in proteins of 'selfish' genetic elements. H...

Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cle…

Toh(Geraldine W-L),Sugawara(Neal),Dong(Junch… DNA Repair (Amst) 2010-11-05

...Slx4 is dispensable for NER but is essential for SSA. Slx4 is phosphorylated by the Mec1 and Tel1 kinases after DNA dama...

Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintain…

Saito(Takamune T),Youds(Jillian L),Boulton(S… PLoS Genet 2010-03-02

...Slx4, as a critical player required in vivo for processing late HR intermediates in Caenorhabditis elegans. DNA damage s...

Repair scaffolding reaches new heights at blocked replication forks.

Downey(Michael),Edenberg(Ellen R),Toczyski(D… Mol Cell 2010-08-20

...Slx4 and Rtt107 with Dpb11 (hTopBP1) in response to MMS-induced DNA alkylation, suggesting that Slx4 and Rtt107 might co...

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