...BRCA2). TRAEs were mostly haematological and most prominent shortly after switching from combination to monotherapy, pro...
...BRCA2. We studied the clinical activity and toxicity of veliparib in ovarian cancer patients carrying a germline BRCA1 o...
...BRCA2 mutations, and also due to new staging standards and use of nuclear magnetic resonance. This increase in the indic...
...BRCA2 nonsense mutation, both of germline origin. The novel BRCA1 mutation induced abnormal splicing, mRNA instability, ...
...BRCA2 and CHECK2 genes associated with breast cancer. The fluorescent label was introduced to the analyzed DNA during PC...
...BRCA2 loss (4 with biallelic somatic loss, and 3 with germline mutations) and 4 of 5 with ATM aberrations. The specifici...
...BRCA2 mutation. None of the precedent case reports describe a chemosensibility to the GEMOX regimen. In spite of the lac...
...BRCA2) can be involved in pathogenesis of hereditary breast cancer which can be explained by incomplete penetrance of BR...
...BRCA2, are known to increase the risk of breast cancer. These heritable mutations are unequally represented among popula...
...BRCA2 gene was associated with 16.5-fold elevated risk (95% CI, 2.2-124.5; P = 2.2 × 10(-4)). Gene-based analyses sugges...
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