...BRCA2 and the Rad51 paralogs are tumor suppressors and critical mediators of Rad51. To gain insight into Rad51 paralog f...
...BRCA2 mutations.,In the studied group 13% (48) of the patients were BRCA mutation carriers. Neutropaenia after the first...
...BRCA2 mutant and three BRCA1 and BRCA2 wild-type (WT) patient-derived pancreatic cancer xenografts.,We observed treatmen...
...BRCA2). TRAEs were mostly haematological and most prominent shortly after switching from combination to monotherapy, pro...
...BRCA2 mutations is widely recommended as part of a risk-reduction strategy for ovarian or breast cancer due to an underl...
...BRCA2 carriers at age 70 years width of 95% CIs: 10% to 35% and 13% to 46%, respectively). Relative bias varied from -38...
...BRCA2 partner DSS1. Biochemical, structural, and in vivo analyses reveal that DSS1 allows the BRCA2-DSS1 complex to phys...
...BRCA2 (ref. 2), ATM, PALB2 (ref. 4), BRCA1 (ref. 5), STK11 (ref. 6), CDKN2A and mismatch-repair genes and low-penetrance...
...BRCA2 and MYC, occurring early in some tumors and late in others. In 13 out of 50 cancers, potentially targetable mutati...
...BRCA2 mutations, 3 (3%) TP53 mutations, 5 (5.1%) DNA mismatch repair gene mutations, 1 (1%) CDH1 mutation, 6 (6.1%) Fanc...
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