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TP53 BRCA1 CRISPR single-cell cancer

Maglione(Katharine D),Margolies(Laurie),Ja... AJR Am J Roentgenol 2015-02-26

...BRCA2 mutation, Klinefelter syndrome) and should be available to those who desire screening, preferably in a clinical tr...

Chai(Kit Man),Wang(Chih-Yen),Liaw(Hung-Jiu... Oncotarget 2015-08-31

We previously found that BRCA1-BRCA2-containing complex subunit 3 (BRCC3) was highly expressed in tumorigenic rat glioma...

Zhong(Qian),Peng(Hong-Ling),Zhao(Xia),Zhan... Clin Cancer Res 2015-09-21

To estimate the effects of BRCA1 and BRCA2 mutations on ovarian cancer and breast cancer survival.,We searched PubMed an...

Xue(Wen-Qiong),He(Yong-Qiao),Zhu(Jin-Hong)... Sci Rep 2015-10-30

BRCA2 gene plays an important role in homologous recombination. Polymorphic variants in this gene has been suggested to ...

Riahi(Aouatef),Kharrat(Maher),Lariani(Imen... Fam Cancer 2015-07-21

Germline deleterious mutations in the BRCA1/BRCA2 genes are associated with an increased risk for the development of bre...

Giannakeas(Vasily),Lubinski(Jan),Gronwald(... Breast Cancer Res Treat 2015-09-21

...BRCA2 carriers. We identified 2,346 women with a BRCA1 (n = 1844) or BRCA2 (n = 502) mutation and no breast cancer, and ...

Davis(Nicole M),Sokolosky(Melissa),Stadelm... Oncotarget 2015-05-12

...BRCA2, EGFR1, PIK3CA, PTEN, TP53, RB as well as other oncogenes and tumor suppressor genes. In some breast cancer cases,...

Brannon Traxler(L),Martin(Monique L),Kerbe... Ann Surg Oncol 2015-06-16

...BRCA2 mutation, and 1 patient was found to carry a variant of uncertain significance.,The introduction of genomics pract...

Pruss(Dmitry),Morris(Brian),Hughes(Elisha)... Breast Cancer Res Treat 2015-09-21

BRCA1 and BRCA2 sequencing analysis detects variants of uncertain clinical significance in approximately 2 % of patients...

Rytelewski(Mateusz),Tong(Jessica G),Buensu... Mol Oncol 2015-08-19

...BRCA2 is involved in homologous recombination repair. BRCA2 defects increase cancer risk but, paradoxically, cancer pati...

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