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TP53 BRCA1 CRISPR single-cell cancer

Girolimetti(Giulia),Perrone(Anna Myriam),S... Biomed Res Int 2015-05-11

...BRCA2 genes. The presence of a BRCA mutation in OC patients has been suggested as a prognostic and predictive factor. In...

Jang(Hyeon-Min),Erf(Gisela F),Rowland(Kayl... BMC Genomics 2015-05-12

...BRCA2, COL12A1, GRM5, LRP2, OBSCN, PLAU, RNF168, STAB2, and XIRP1. Intermolecular gene network analysis revealed that ca...

Risbridger(Gail P),Taylor(Renea A),Clousto... Eur Urol 2015-12-02

...BRCA2 and BRCAX patients were determined using Kaplan-Meier analysis.,PDXs from BRCA2 tumours showed increased incidence...

Anders(Carey),Deal(Allison M),Abramson(Van... Breast Cancer Res Treat 2015-03-30

...BRCA2). Median TTP was 2.14 months and median OS was 7.8 months. Intracranial RR was 12 %, while intracranial CBR was 27...

Davis(Nicole M),Sokolosky(Melissa),Stadelm... Oncotarget 2015-05-12

...BRCA2, EGFR1, PIK3CA, PTEN, TP53, RB as well as other oncogenes and tumor suppressor genes. In some breast cancer cases,...

Brannon Traxler(L),Martin(Monique L),Kerbe... Ann Surg Oncol 2015-06-16

...BRCA2 mutation, and 1 patient was found to carry a variant of uncertain significance.,The introduction of genomics pract...

Jia(Haiying),Guo(Yunfei),Zhao(Weiwei),Wang... Sci Rep 2015-11-02

...BRCA2 (84.2 kb) genes from nine subjects and sequenced them on an Illumina MiSeq sequencer. We found that the TaKaRa Pri...

Riahi(Aouatef),Kharrat(Maher),Lariani(Imen... Fam Cancer 2015-07-21

Germline deleterious mutations in the BRCA1/BRCA2 genes are associated with an increased risk for the development of bre...

Pruss(Dmitry),Morris(Brian),Hughes(Elisha)... Breast Cancer Res Treat 2015-09-21

BRCA1 and BRCA2 sequencing analysis detects variants of uncertain clinical significance in approximately 2 % of patients...

Watkins(Johnathan A),Irshad(Sheeba),Grigor... Breast Cancer Res 2015-04-16

...BRCA2 genes, the products of which contribute to the conservative homologous recombination repair of DNA double-strand b...

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