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Clinical Impact of Germline Pathogenic Variants in High-risk Prostate Cancer ...

Galego-Carro(J),Santamariña(M),Blanco-Pére... Eur Urol Open Sci 2026-09-00

...BRCA2 variants were significantly enriched in patients compared with non-cancer control cohorts. BRCA1/BRCA2 carriers ha...

Characterization of putative germline pathogenic variants in 27 candidate can...

Ikeda(N),Mizukami(K),Yamada(R),Toyoda(H),A... Sci Rep 2026-08-08

...BRCA2, RAD51C, or ATM) and two cats with those in mismatch repair genes (MSH2 and MSH6) may be candidates for targeted t...

Hormone replacement therapy in healthy BRCA1 and 2 mutation carriers after ri...

Bounous(VE),Andronico(N),Lavalle(G),Suraci... Maturitas 2026-09-00

...BRCA2 mutations is clinically challenging, particularly in those undergoing risk-reducing salpingo-oophorectomy. This pr...

Somatic BRCA1 and BRCA2 detection in homologous recombination deficiency test...

Scaglione(GL),Roma(C),Califano(D),Cecere(S... Int J Gynecol Cancer 2026-06-20

To assess concordance of tumor BRCA1/BRCA2 variant detection across four sequencing workflows benchmarked against the My...

Prostate cancer initially misdiagnosed as prostatic abscess in a 36-year-old ...

Xiaomin(X),Gang(W),Li(T),Zhenhua(X),Guobin... Curr Ther Res Clin Exp 2026-12-00

...BRCA2, ATM, and TP53 mutations. He underwent 3D laparoscopic radical prostatectomy with a modified surgical approach to ...

Chemotherapy type and survival in young BRCA1/2 carriers with HER2-negative e...

Bernstein-Molho(R),Sella(T),Delucchi(V),Co... Eur J Cancer 2026-09-09

...BRCA2 pathogenic variants (BRCA carriers) with early breast cancer (BC) is limited. We evaluated the association of diff...

Real-world clinical outcomes of patients with early-stage TNBC and BRCAm who ...

Lynce(F),Ru(M),Luo(L),Miranda(M),Xu(X),Isa... Breast Cancer Res Treat 2026-08-12

...BRCA2 mutation (BRCAm) is not well characterized. This retrospective, observational study explored the real-world effect...

BRCA Testing in Prostate Cancer: A Histopathologist's Perspective.

Sanguedolce(F),Mazzucchelli(R),Conteduca(V... Diagnostics (Basel) 2026-07-27

...BRCA2 alterations, are characterized by adverse clinicopathological features, including a higher grade and stage at diag...

Pathologist-recommended molecular testing in endometrial cancer: A single-ins...

Mills(AM),Vidis(L),Carlson(DK),Crawford(MP... Hum Pathol 2026-08-18

...BRCA2 mutation leading to confirmation of a germline syndrome and an MMR-deficient malignancy with TSC2 alterations whic...

Case Report: Personalized therapy in gynecological neuroendocrine neoplasm: a...

Mantiero(M),Polignano(M),Bassetti(A),Oldan... Front Oncol None

...BRCA2 mutation. Patient achieved a pathological complete response following platinum-based chemotherapy and subsequently...

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