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Assessment of changes in the BRCA2 and P53 genes in breast invasive ductal ca...

Ramalho(Eduardo Avf),Silva-Filho(João Lq),... Biol Res 2015-04-22

...BRCA2 methylation frequency was 44%, p53 Pro22 allele frequency was 32% and heterozygous frequency of Arg/Pro72 genotype...

Nipple-sparing mastectomy in BRCA1/2 mutation carriers: an interim analysis a...

Yao(Katharine),Liederbach(Erik),Tang(Rong)... Ann Surg Oncol 2015-09-24

...BRCA2 mutation; 150 (74.6 %) patients underwent NSM for risk reduction and 51 (25.4 %) for cancer. Incidental cancers we...

BRCA1/2 germline mutations and their clinical importance in Turkish breast ca...

Cecener(Gulsah),Egeli(Unal),Tunca(Berrin),... Cancer Invest 2015-01-06

...BRCA2;V2466A) related with disease. Our findings contribute significantly to the types of germline BRCA1/BRCA2 mutations...

Tissue-specific effects of valproic acid on DNA repair genes and apoptosis in...

Lamparter(Christina),Winn(Louise M) Toxicol Sci 2015-10-23

...Brca2, with Western blotting used to quantify Rad51, cleaved caspase-3 and cleaved-PARP protein. Increased recombination...

MicroRNA expression signatures for the prediction of BRCA1/2 mutation-associa...

Tanic(Miljana),Yanowski(Kira),Gómez-López(... Int J Cancer 2015-01-23

...BRCA2 is indicated for patients with breast cancer from high-risk breast cancer families and influences both treatment o...

Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict b...

Vollebergh(Marieke A),Lips(Esther H),Neder... Breast Cancer Res 2015-04-16

...BRCA2-mutated breast cancers can identify breast cancer patients with TN as well as ER-positive, HER2-negative tumors th...

Applications for breast magnetic resonance imaging.

Pilewskie(Melissa),Morrow(Monica) Surg Oncol Clin N Am 2015-02-12

...BRCA2 mutations, a family history suggesting a hereditary breast cancer syndrome, or a history of chest wall radiation.

VEGFR3 inhibition chemosensitizes ovarian cancer stemlike cells through down-...

Lim(Jaeyoung J),Yang(Kun),Taylor-Harding(B... Neoplasia 2015-01-23

...BRCA2. Inhibition of VEGFR3 in ovarian tumor cells was associated with growth arrest. CD133(+) ovarian cancer stemlike c...

Breast cancer: major risk factors and recent developments in treatment.

Majeed(Wafa),Aslam(Bilal),Javed(Ijaz),Khal... Asian Pac J Cancer Prev 2015-01-06

...BRCA2 genes. Obesity, hormone therapy and use of alcohol are possible causes and over-expression of leptin in adipose ti...

Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familia...

De Silva(Sumadee),Tennekoon(Kamani Hemamal... BMC Res Notes 2015-01-20

...BRCA2 rearrangement was also identified in the cohort.,Thus this study demonstrates that BRCA1 and BRCA2 large genomic r...

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