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TP53 BRCA1 CRISPR single-cell cancer

Junes-Gill(Katiana S),Lawrence(Chris E),Wh... BMC Cancer 2015-07-14

...BRCA2 (r = -0.224, P < 0.0005), ADAMTS1 (r = -0.132, P <0.01) and endostatin (r = 0.141, P < 0.005).,hHSS1-overexpressio...

Oza(Amit M),Cibula(David),Benzaquen(Ana Oa... Lancet Oncol 2015-04-01

...BRCA2 mutations. The aim of this study was to assess the efficacy and tolerability of olaparib in combination with chemo...

Reuter(Marcel),Zelensky(Alex),Smal(Ihor),M... J Cell Biol 2015-03-03

...BRCA2 existed in oligomeric clusters, and exhibited heterogeneous mobility. DNA damage increased BRCA2 transient binding...

Powell(C Bethan) Curr Opin Obstet Gynecol 2015-08-31

...BRCA2 mutations, and third, the 'ovarian cancers' associated with BRCA mutations actually include fallopian tube and per...

Carlucci(A),D'Angiolella(V) Br J Cancer 2015-04-23

Mutations in the BRCA1 and BRCA2 genes predispose individuals to the development of breast and ovarian cancers. As a res...

Deb(S),Wong(S Q),Li(J),Do(H),Weiss(J),Byrn... Br J Cancer 2015-04-16

...BRCA2 germline mutant and 28 BRCAX) for hotspot somatic mutations and copy number changes in 48 common cancer genes.,Twe...

Lee(MiYoung),Venkitaraman(Ashok R) Cell Cycle 2015-08-19

...BRCA2, implicated in the abscission step of cytokinesis. Indeed, expression of this C-terminal HMG20b region suffices to...

Zhao(Xiaohong),Zhou(Yan),Nie(Mingchao),Xia... Tumour Biol 2015-07-09

...BRCA2, has been reported to be amplified in ovarian cancer. However, the expression pattern and biological functions of ...

Elnar(Arpiné Ardzivian),Desor(Frédéric),Ma... Toxicology 2015-03-25

...Brca2, Fancd2, Figf, Mycn, p53 and Rad51 was observed between groups (p<0.001). Finally, using immunoblots we determined...

Domínguez-Gómez(G),Díaz-Chávez(J),Chávez-B... Oncol Rep 2015-08-20

...BRCA2-deficient cell lines. The aim of this study was to analyze the effect of the PARP inhibitor nicotinamide (NAM) on ...

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