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TP53 BRCA1 CRISPR single-cell cancer

Lee(MiYoung),Venkitaraman(Ashok R) Cell Cycle 2015-08-19

...BRCA2, implicated in the abscission step of cytokinesis. Indeed, expression of this C-terminal HMG20b region suffices to...

Zhao(Xiaohong),Zhou(Yan),Nie(Mingchao),Xia... Tumour Biol 2015-07-09

...BRCA2, has been reported to be amplified in ovarian cancer. However, the expression pattern and biological functions of ...

Elnar(Arpiné Ardzivian),Desor(Frédéric),Ma... Toxicology 2015-03-25

...Brca2, Fancd2, Figf, Mycn, p53 and Rad51 was observed between groups (p<0.001). Finally, using immunoblots we determined...

Domínguez-Gómez(G),Díaz-Chávez(J),Chávez-B... Oncol Rep 2015-08-20

...BRCA2-deficient cell lines. The aim of this study was to analyze the effect of the PARP inhibitor nicotinamide (NAM) on ...

Jaspers(Janneke E),Sol(Wendy),Kersbergen(A... Cancer Res 2015-04-13

...BRCA2-associated hereditary breast cancer to study drug resistance to several types of chemotherapy and PARP inhibition....

Grant(Robert C),Selander(Iris),Connor(Asht... Gastroenterology 2015-04-14

We investigated the prevalence of germline mutations in APC, ATM, BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, P...

De Pascalis(Ivana),Pilato(Brunella),Mazzot... Oncol Rep 2015-08-11

...BRCA2 mutation analysis. For these reasons, we stratified the 22 familial BC patients in two group: 'low-risk' (n=11) an...

Arai(Masami),Iwase(Takuji),Takazawa(Yutaka... Gan To Kagaku Ryoho 2015-01-20

...BRCA2. Although the frequency is low, genomic rearrangement is also found in Japan; therefore, in addition to PCR-direct...

Churpek(Jane E),Walsh(Tom),Zheng(Yonglan),... Breast Cancer Res Treat 2015-09-28

...BRCA2 genes and 20 % (13/65) carried mutations in PALB2, CHEK2, BARD1, ATM, PTEN, or TP53. The mutational allelic spectr...

Ghosh(Soma),Bhunia(Anil K),Paun(Bogdan C),... Hum Mutat 2015-10-02

...BRCA2 exon 27 shotgun-mutant plasmids including solitary and multiplex mutations to generate human knockin clones using ...

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