...BRCA2 genes. Less common susceptibility genes also are associated with increased risk for developing breast cancer, but ...
...BRCA2 and Rad51. PJ34 significantly increased the ratio of γH2AX-positive cells and the number of foci/cells. The comet ...
...BRCA2 mutations. These findings suggest that genomic catastrophes have a significant role in the malignant transformatio...
...BRCA2 (BRCA) testing in sporadic breast cancer patients. Limited family structure has been proposed as a predictor of BR...
...BRCA2 (BRCA1/2) -associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum o...
Germline mutations in the BRCA1 and BRCA2 genes confer an estimated 58% to 80% lifetime risk of breast cancer. In genera...
...BRCA2, BRIP1, CHEK2, PALB2, RAD50, RAD51C, RAD80, and TP53) from promoter to 3'-UTR in 24 patients simultaneously. This ...
...BRCA2 increase susceptibility to breast, ovarian and prostate cancers. The product of human BRCA2, BRCA2 protein, has a ...
...BRCA2, PALB2, CHEK2, and other genes involved in DNA repair. However, most families severely affected by breast cancer d...
...BRCA2 mutations. Since the development of first-generation PARP inhibitors more than a decade ago, numerous clinical tri...
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