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53BP1 regulates DSB repair using Rif1 to control 5' end resection.

Zimmermann(Michal),Lottersberger(Francisca... Science 2013-02-20

...BARD1 complexes at sites of DNA damage; and defines one of the mechanisms by which 53BP1 causes chromosomal abnormalitie...

Blood cellular mutant LXR-α protein stability governs initiation of coronary ...

Arora(Mansi),Kaul(Deepak),Sharma(Yash Paul... World J Cardiol 2013-09-06

To investigate the role of [breast and ovarian cancer susceptibility 1 (BRCA1)-associated RING domain 1 (BARD1)]/BRCA1 E...

Hypermethylation of TUSC5 genes in breast cancer tissue.

Bubnov(V),Moskalev(E),Petrovskiy(Y),Bauer(... Exp Oncol 2013-11-06

...BARD1, AKR1C2, TP53INK1 and others. Analysis of DNA methylation of TUSC5 by COBRA revealed higher levels of exon 1 methy...

The genetic landscape of high-risk neuroblastoma.

Pugh(Trevor J),Morozova(Olena),Attiyeh(Edw... Nat Genet 2013-05-30

...BARD1. The relative paucity of recurrent somatic mutations in neuroblastoma challenges current therapeutic strategies th...

Replication of GWAS-identified neuroblastoma risk loci strengthens the role o...

Capasso(Mario),Diskin(Sharon J),Totaro(Fra... Carcinogenesis 2013-04-19

...BARD1 (P = 8.4 × 10(-15)). BARD1 showed an additional and independent SNP association (rs7585356). This variant influenc...

Luring BRCA1 to the scene of the crime.

Baer(Richard) Cancer Cell 2013-07-22

...BARD1 and poly(ADP-ribose) chains at the DSB.

Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation.

Li(Mo),Yu(Xiaochun) Cancer Cell 2013-07-22

...BARD1 as a poly(ADP-ribose) (PAR)-binding module. The binding of the BARD1 BRCTs to PAR targets the BRCA1/BARD1 heterodi...

The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Fu...

Henderson(Beric R) Scientifica (Cairo) 2013-11-26

...BARD1 and further modulated by cancer mutations and diverse signaling pathways. This paper will focus on the transport, ...

Common variation at BARD1 results in the expression of an oncogenic isoform t...

Bosse(Kristopher R),Diskin(Sharon J),Cole(... Cancer Res 2012-06-01

...BARD1β. In neuroblastoma cells, silencing of BARD1β showed genotype-specific cytotoxic effects, including decreased subs...

BARD1 expression predicts outcome in colon cancer.

Sporn(Judith C),Hothorn(Torsten),Jung(Barb... Clin Cancer Res 2012-02-03

BARD1 is a BRCA1-binding partner with tumor suppressive properties. Aberrant splice variants of BARD1 have been detected...

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