文献库搜索 | GeneLibs

Nizamuddin(N),Biswas(S),Zawar(A),Deshpande... Front Syst Biol None

...BRCA2 variants from the BRCA Exchange database, completely independent of the ClinVar training data demonstrated an over...

Viveros-Carreño(D),Mora-Soto(N),Beshar(I),... Int J Gynecol Cancer 2026-08-03

...BRCA2 remain the highest-impact tubo-ovarian cancer predisposition genes, but Lynch syndrome genes, BRIP1, RAD51C, RAD51...

Guo(YR),Liu(C),Bai(X),Li(KC),Zhao(JB),Lin(... J Pathol 2026-08-20

...BRCA2), and mismatch repair genes (MLH1, MSH2, MSH6). Collectively, our findings identified SMARCA4 deficiency as a pred...

Liu(B),Michel(AM),Mundi(PS),Sigel(KM),Bate... Oncologist 2026-08-06

...BRCA2 mutations, and conditions that promote hormonal imbalance and excess estrogen exposure, such as obesity and hepati...

Lai(E),Pierantoni(F),Zampiva(I),Bimbatti(D... Cancers (Basel) 2026-07-25

...BRCA2 (12.5%), ATM (3.1%), and BRCA1 (1.39%) being the most common alterations. A family history of breast, ovarian, or ...

Abdel-Razeq(H),Bani Hani(H),Alafeef(S),Tam... Front Oncol None

...BRCA2, and TP53; no BRCA1 P/LP variants were identified. Germline P/LP variants are common in young male patients with c...

Steenbock(O),Rieger(C),Heidenreich(J),Paff... Urol Int 2026-08-13

...BRCA2 mutations (Genomic ScarScore GSS) using the HANDLE HRD Focus Panel. The data were evaluated using the following th...

Kapoor(A),Uthale(S),Chain(A),Rungta(A),Ano... JCO Glob Oncol 2026-08-00

...BRCA2, PALB2, RAD51C, RAD51D, ATM, CHEK2, BRIP1, BARD1, RAD50, NBN, MRE11, and FANCC. Of 950 patients analyzed, 364 (38....

Kamau(K),Byrne(L),Goradia(R),Sundi(D),Meng... Eur Urol Oncol 2026-08-13

...BRCA2, and ATM. Very small cohorts of patients with UC and LS or a DDR variant responded well to immune checkpoint inhib...

Shore(N),Clarke(NW),Armstrong(AJ),Oya(M),P... Eur Urol Oncol 2026-08-13

...BRCA2 (7.3%), ATM (6.2%), and CDK12 (5.0%). HRs numerically favored olaparib plus abiraterone for rPFS (BRCA2, HR, 0.20;...