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TP53 BRCA1 CRISPR single-cell cancer

McLuckie(Keith I E),Di Antonio(Marco),Zecc... J Am Chem Soc 2014-02-07

...BRCA2-deficient cells that are genetically impaired in homologous recombination-mediated DSB repair. G4 targeting ligand...

Kobayashi(Hiroshi),Ohno(Sumire),Sasaki(Yos... Oncol Rep 2014-06-12

...BRCA2 (BRCA) genes are responsible for the majority of HBOC syndrome. Lifetime cancer risks in BRCA mutation carriers ar...

Brandão(R D),van Roozendaal(K),Tserpelis(D... Hum Reprod 2014-03-03

...BRCA2-deficiency also results in impaired oogenesis. A recent study has reported that the POI in BRCA1/2-mutation carrie...

Singer(C F),Muhr(D),Rappaport(C),Tea(M-K),... Clin Genet 2014-07-18

The objective of this study was to describe the experience of genetic testing in Austrian women with a BRCA1 or BRCA2 mu...

Moorman(Patricia G),Havrilesky(Laura J),Gi... J Clin Oncol 2014-01-23

...BRCA2 mutation carriers separately. Data were inadequate to perform meta-analyses examining duration or timing of use. F...

Huang(Yi-Yuan),Dai(Li),Gaines(Dakim),Droz-... Cancer Res 2014-02-25

...BRCA2-interacting protein BCCIP as the platform, we found that a conditional BCCIP knockdown and concomitant p53 deletio...

Ko(Kwang-Pil),Kim(Sung-Won),Ma(Sung Hyun),... Am J Clin Nutr 2014-04-07

...BRCA2 mutation carriers. In the analysis with only cases, the highest quartile of soy intake, but not meat intake, was a...

Nikkilä(Jenni),Parplys(Ann Christin),Pylkä... Nat Commun 2014-06-12

Besides mutations in BRCA1/BRCA2, heterozygous defects in PALB2 are important in breast cancer predisposition. PALB2 het...

Tanic(M),Andrés(E),Rodriguez-Pinilla(S M),... Br J Cancer 2014-01-06

...BRCA2, along with rare intermediate-risk genes and common low-penetrance alleles identified, altogether explain no more ...

Enginler(S O),Akış(I),Toydemir(T S F),Ozta... Vet Res Commun 2014-05-22

...BRCA2 are the most important genes significantly associated with mammary tumours. The aim of this study was to determine...

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