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Patient-reported hereditary breast and ovarian cancer in a primary care pract...

Quillin(John M),Krist(Alexander H),Gyure(M... J Community Genet 2014-03-17

...BRCA2 counseling referral in a primary care setting, (2) explore associations with high-risk status and various patient ...

Double heterozygosity in the BRCA1 and BRCA2 genes in Italian family.

Vietri(Maria Teresa),Molinari(Anna Maria),... Clin Chem Lab Med 2014-10-06

...BRCA2 and a novel variant IVS4-57A>G (c.426-57A>G) in BRCA2, not previously described. Both mutations were inherited fro...

Regulators of global genome repair do not respond to DNA damaging therapy but...

Bowden(Nikola A),Ashton(Katie A),Vilain(Ri... PLoS One 2014-03-05

...BRCA2, ATM and CHEK2 showed altered expression in melanoma cell lines after cisplatin treatment. In melanoma tumour tiss...

Hereditary genes and SNPs associated with breast cancer.

Mahdi(Kooshyar Mohammad),Nassiri(Mohammad ... Asian Pac J Cancer Prev 2014-02-19

...BRCA2, PTEN, ATM, TP53, CHEK2, PPM1D, CDH1, MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, PMS1, PMS2, BRIP1, RAD50, RAD51C, STK11...

BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of hum...

Shen(Yuqiao),Rehman(Farah L),Feng(Ying),Bo... Clin Cancer Res 2014-09-01

...BRCA2, or PTEN gene defects with 20- to more than 200-fold greater potency than existing PARP1/2 inhibitors. BMN 673 is ...

Differential chemotherapeutic sensitivity for breast tumors with "BRCAness": ...

Chalasani(Pavani),Livingston(Robert) Oncologist 2014-05-06

BRCA1 or BRCA2 mutations predispose to cancer development, primarily through their loss of role in the repair of DNA dou...

Mutation analysis of the BCCIP gene for breast cancer susceptibility in breas...

Bonache(Sandra),Gutierrez-Enriquez(Sara),T... Gynecol Oncol 2014-01-06

...BRCA2 protein and is required for BRCA2 stability and function, making a critical contribution to the function of BRCA2 ...

Ovarian cancer genome.

Imyanitov(Evgeny N) Methods Mol Biol 2014-03-17

...BRCA2, RAD51C, NBN (NBS1), BRIP, and PALB2. Sporadic ovarian cancers often phenocopy the features of BRCA1-related hered...

Five-year analysis of magnetic resonance imaging as a screening tool in women...

Kam(Jeffrey K P),Naidu(Paayal),Rose(Alliso... J Med Imaging Radiat Oncol 2014-01-24

...BRCA2 mutation carriers, and one was found to be a carrier after the cancer was diagnosed. All four were identified as s...

ZNF365 promotes stalled replication forks recovery to maintain genome stability.

Zhang(Yuqing),Park(Eunmi),Kim(Christopher ... Cell Cycle 2014-03-20

...BRCA2, which are important molecules required for DNA damage response. Previously, we demonstrated that ZNF365 is necess...

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