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TP53 BRCA1 CRISPR single-cell cancer

Chakraborty(Sandeep) F1000Res 2014-03-14

...BRCA2 tumor suppressor protein leave individuals susceptible to breast, ovarian and other cancers. The BRCA2 protein is ...

Wiedemeyer(W Ruprecht),Beach(Jessica A),Ka... Front Oncol 2014-06-24

...BRCA2 in particular, as main determinants of response to platinum therapy. BRCA-mutant ovarian cancers are especially se...

Cury(Nathalia M),Ferraz(Victor Ef),Silva(W... Hered Cancer Clin Pract 2014-03-20

...BRCA2 genes and is characterized by breast adenocarcinoma and/or epithelial ovarian carcinoma. LFS is associated with ge...

Wasson(Mishi Kaushal),Chauhan(Pradeep Sing... Tumour Biol 2014-08-19

...BRCA2, and CCND1-G870A were examined in 204 BC cases and 217 controls from Northeast Indian population. Multifaceted ana...

Hou(Jing),Wang(Ziliang),Yang(Lina),Guo(Xia... Tumour Biol 2014-08-19

...BRCA2 and to inactivate the function of BRCA2, leading to the development of sporadic breast and ovarian cancers. The fu...

Killick(Emma),Tymrakiewicz(Malgorzata),Cie... PLoS One 2014-09-29

...BRCA2 mutation carriers and controls. The first group was a prospective set of 665 male BRCA1/2 mutation carriers and co...

Whiley(Phillip J),Parsons(Michael T),Leary... PLoS One 2014-12-22

Rare exonic, non-truncating variants in known cancer susceptibility genes such as BRCA1 and BRCA2 are problematic for ge...

Shive(Heather R),West(Robert R),Embree(Lis... PLoS One 2014-10-06

...BRCA2 and TP53 significantly influence human cancer risk, and cancers from humans who inherit one mutant allele for BRCA...

Buisson(Rémi),Niraj(Joshi),Pauty(Joris),Ma... Cell Rep 2014-10-08

...BRCA2, and Polη colocalize at stalled or collapsed replication forks after hydroxyurea treatment. Moreover, PALB2 and BR...

Cunningham(J M),Cicek(M S),Larson(N B),Dav... Sci Rep 2014-10-10

We evaluated homologous recombination deficient (HRD) phenotypes in epithelial ovarian cancer (EOC) considering BRCA1, B...

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