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Missense mutations (p.H371Y, p.D438Y) in gene CHEK2 are associated with breas...

Baloch(Abdul Hameed),Daud(Shakeela),Raheem... Mol Biol Rep 2014-09-29

...BRCA2. Multiple studies have shown that a CHEK2*1100delC confers about a two-fold increased risk of breast cancer in uns...

Development of breast tumors in CHEK2, NBN/NBS1 and BLM mutation carriers doe...

Suspitsin(Evgeny N),Yanus(Grigory A),Sokol... Med Oncol 2014-08-14

...BRCA2 mutation carriers, which determines their unprecedented sensitivity to some DNA-damaging agents. Data on tumor-spe...

Comprehensive sequencing of PALB2 in patients with breast cancer suggests PAL...

Fernandes(Priscilla H),Saam(Jennifer),Pete... Cancer 2014-07-10

...BRCA2 based on their personal and family history, and a "lower-risk" group consisting of 524 samples from patients with ...

Natural and glucosyl flavonoids inhibit poly(ADP-ribose) polymerase activity ...

Maeda(Junko),Roybal(Erica J),Brents(Collee... Oncol Rep 2014-09-03

...BRCA2 gene (V-C8) and its parental V79 cells showed BRCA2-dependent synthetic lethality when treated with the flavonoids...

Ovarian cancer familial relative risks by tumour subtypes and by known ovaria...

Jervis(Sarah),Song(Honglin),Lee(Andrew),Di... J Med Genet 2014-09-08

...BRCA2 was estimated to be over twice that of the general population (2.24 (95% CI 1.71 to 2.94)). BRCA1 and BRCA2 mutati...

Reproductive factors and breast cancer risk among BRCA1 or BRCA2 mutation car...

Pan(Hong),He(Zhongyuan),Ling(Lijun),Ding(Q... Cancer Epidemiol 2014-11-02

...BRCA2 mutation carriers. This meta-analysis is the first to be performed to determine the relationship between reproduct...

Outcome of unexpected adnexal neoplasia discovered during risk reduction salp...

Conner(James R),Meserve(Emily),Pizer(Ellen... Gynecol Oncol 2014-04-11

This study computed the risk of clinically silent adnexal neoplasia in women with germ-line BRCA1 or BRCA2 mutations (BR...

Mismatch repair deficiency in ovarian cancer -- molecular characteristics and...

Xiao(Xue),Melton(David W),Gourley(Charlie) Gynecol Oncol 2014-04-11

...BRCA2 mutations. While there has been extensive investigation of MMR deficiency in colorectal cancer, MMR in ovarian can...

Transformation of the fallopian tube secretory epithelium leads to high-grade...

Perets(Ruth),Wyant(Gregory A),Muto(Katheri... Cancer Cell 2014-02-11

...BRCA2 mutations.

Effect of BRCA1 on epidermal growth factor receptor in ovarian cancer.

Li(Da),Bi(Fang-Fang),Cao(Ji-Min),Cao(Chen)... J Exp Clin Cancer Res 2014-09-26

...BRCA2-mutated or not, and 22 pairs with hypermethylated BRCA1 promoter or not). BRCA1 promoter methylation was analyzed ...

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