Missense variants in the BRCA2 gene are routinely detected during clinical screening for pathogenic mutations in patient...
...BRCA2 levels (P=0.03) and a worse PFS, and between high nibrin levels and a worse OS (P=0.006).,Our results indicate tha...
...BRCA2) gene variants known to alter splicing (BRCA1: c.135-1G>T, c.591C>T, c.594-2A>C, c.671-2A>G, and c.5467+5G>C and B...
...BRCA2 mutation carriers.,Prospective follow-up of female carriers of BRCA1 or BRCA2 mutations who had no personal histor...
...BRCA2, CD44, RASSF1, DAPK1, FHIT, VHL, ESR1, TP73, IGSF4, GSTP1 and CDH13) in primary lesions to obtain information abou...
...BRCA2, sensitize tumor cells to poly(ADP-ribose) polymerase (PARP) inhibitors. The ataxia telangiectasia mutated (ATM) k...
...BRCA2/FANCD1-null, and PALB2/FANCN-null phenotypes was confirmed by uniform tumor regression on single-dose cross-linker...
...BRCA2 in unaffected women to identify those at significantly elevated risk for developing breast and ovarian cancers, an...
...BRCA2 mutations is heterogeneous in diverse populations. 185AGdel and 5382insC are the most important BRCA1 and BRCA2 al...
...BRCA2 insufficiency is associated with breast cancer development; however, in sporadic breast cancer cases, high BRCA2 e...
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