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TP53 BRCA1 CRISPR single-cell cancer

Purrington(Kristen S),Slager(Susan),Eccles... Carcinogenesis 2014-06-24

...BRCA2, RAD51L1-rs2588809, MKL1). Further, two SNPs independent of previously reported signals in ESR1 [rs12525163 odds r...

Ingham(Sarah L),Sperrin(Matthew),Baildam(A... Breast Cancer Res Treat 2014-07-18

...BRCA2. 105 BRCA1 carriers and 122 BRCA2 carriers developed breast cancer during follow-up. The hazard of death was stati...

Joshi(Poorval M),Sutor(Shari L),Huntoon(Ca... J Biol Chem 2014-05-21

Mutations in the tumor suppressors BRCA1 and BRCA2, which encode proteins that are key participants in homologous recomb...

Melchor(Lorenzo),Molyneux(Gemma),Mackay(Al... J Pathol 2014-07-10

...Brca2, Pten and p53 were depleted in either basal mammary epithelial cells or luminal oestrogen receptor (ER)-negative c...

Hoskins(Lindsey M),Werner-Lin(Allison),Gre... PLoS One 2014-11-04

...BRCA2 face a unique set of challenges related to managing cancer risk during a demographically-dense stage of life. They...

Raphael(J),Mazouni(C),Caron(O),Ferchiou(M)... Med Oncol 2014-09-30

...BRCA2 patients and 13 (19%) WT patients (p=0.43). Twenty (69%) BRCA2 carriers and 34 (51%) WT patients remained node-pos...

Schwartz(Marc D),Valdimarsdottir(Heiddis B... J Clin Oncol 2014-04-21

...BRCA2 gene testing, genetic counseling is increasingly offered by telephone. As genomic testing becomes more common, eva...

Prensner(John R),Chen(Wei),Iyer(Matthew K)... Cancer Res 2014-05-08

...BRCA2 tumor suppressor, which, in turn, imparts a high sensitivity to small-molecule inhibitors of PARP1. These effects ...

Yahia(Zeinab A),Adam(Ameera Am),Elgizouli(... Infect Agent Cancer 2014-03-17

...BRCA2 in Sudanese breast cancer patients, the methylation status of six tumor suppressor genes was investigated using me...

Hou(Jing),Wang(Ziliang),Yang(Lina),Guo(Xia... Tumour Biol 2014-08-19

...BRCA2 and to inactivate the function of BRCA2, leading to the development of sporadic breast and ovarian cancers. The fu...

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