...BRCA2 genes may be considered a useful pre-operative tool for the differential diagnosis of pelvic masses.
Two major high-penetrance breast cancer genes, BRCA1 and BRCA2, are responsible for approximately 20% of hereditary brea...
...BRCA2 to the problem of assessing candidate genes using rare missense substitution data observed in case-control mutatio...
...BRCA2 mutation had been identified in their family. Data collection consisted of an audio recorded, semi-structured inte...
...BRCA2 mutations are hypersensitive to inhibition of poly(ADP-ribose) polymerase-1 (PARP-1). We recently showed that inte...
...BRCA2 from 24 primate species and find that this gene has also evolved under positive selection.,While mutations leading...
...BRCA2 to RPA-bound nuclear foci in cells experiencing replication stress. Phosphorylated RPA also stimulated recruitment...
...BRCA2 mutation carriers by sequencing all exons of BRCA2 in a German cohort of 382 familial PrCa cases and of 92 sporadi...
...BRCA2 are the most important genes significantly associated with mammary tumours. The aim of this study was to determine...
BRCA2 mutations are significantly associated with early-onset breast cancer, and the tumour-suppressing function of BRCA...
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