...BRCA2, which are essential in maintaining genomic stability. In this study, we describe the lead optimization of a 1,4-t...
...BRCA2 carriers) underwent NSM and immediate breast reconstruction at Peking University International Hospital from Janua...
...brca2 genes to improve vascular endothelial cell proliferation and migration in zebrafish. In summary, our findings sugg...
...BRCA2 gene was the most frequently mutated (n = 3, 27.3%). Whole exome sequencing showed candidate genes, such as FBXO24...
...BRCA2-deficient Capan-1 cells. Compared with monotherapy, combination therapy markedly enhanced apoptosis and suppressed...
...BRCA2-mutated mHSPC. Positive results have also recently been obtained from the phase III TALAPRO-3 trial; talazoparib a...
...BRCA2-associated cancer risk, where current risk-identification strategies have been shown to miss greater than 70% of a...
...BRCA2 and Brh2, the BRCA2 orthologue in Ustilago maydis, enable recombinational repair of DNA by controlling Rad51. In t...
...BRCA2, CHEK2, PALB2). Disease recurrence occurred in 30%. Median follow-up was 53 months. Median disease-free survival (...
...BRCA2. However, the mechanistic details of how RAD52 substitutes for BRCA2 functions are only beginning to emerge. RAD52...
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