...BRCA2 mutations. The patient with the intraductal papillary mucinous neoplasm had Peutz-Jeghers syndrome. All 3 patients...
...BRCA2, PALB2, and SPARC so as to determine their influence on tumor response on targeted therapies. As research progress...
...BRCA2-binding partner protein that represses the DNA repair function of BRCA2 in non-hereditary breast cancer. Although ...
...BRCA2 tumor suppressor protein leave individuals susceptible to breast, ovarian and other cancers. The BRCA2 protein is ...
...BRCA2 genes and is characterized by breast adenocarcinoma and/or epithelial ovarian carcinoma. LFS is associated with ge...
Identification of the 10% to 15% of patients with ovarian cancer who have germline BRCA1 or BRCA2 mutations is important...
...BRCA2-mutated and BRCA2-mutated ovarian cancer compared to their normal tissues; BRCA1 repression (BRCA1 mutation or BRC...
...BRCA2 tumor suppressors to DNA damage foci through multivalent binding of Lys-63-linked polyubiquitin chains. Mutations ...
...BRCA2 in particular, as main determinants of response to platinum therapy. BRCA-mutant ovarian cancers are especially se...
...BRCA2 mutations, but for women without such mutations, the decision to remove the contralateral breast is controversial....
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