...BRCA2 insufficiency is associated with breast cancer development; however, in sporadic breast cancer cases, high BRCA2 e...
...BRCA2 testing which has become part of clinical practice for more than a decade. Currently predictive BRCA1/BRCA2 testin...
...BRCA2 and PALB2 (one tumour each), as well as in genes altered in extra-pancreatic neoplasms, such as JAK1 in four tumou...
...BRCA2 was estimated to be over twice that of the general population (2.24 (95% CI 1.71 to 2.94)). BRCA1 and BRCA2 mutati...
...BRCA2 (pS3291-BRCA2) to limit stabilizing contacts with polymerized RAD51; however, how replication stress modulates CDK...
...BRCA2 carriers, 3.5%; and noncarriers, 0.5%; P < .001). In multivariable models, positive BRCA1/2 mutation status (P = ....
...BRCA2-related cancers. In our cohort, both clearly pathogenic mutations were identified in premenopausal breast cancer c...
...BRCA2 are sensitive to PARG depletion or inhibition. These data raise the exciting possibility that PARG inhibitors may ...
...BRCA2 carriers, we genotyped these SNPs in 12,599 BRCA1 and 7,132 BRCA2 mutation carriers and analysed the associations ...
...BRCA2 mutations.,The median numbers of total and rare CNVs per genome were not different between controls and patients. ...
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