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Cost-effectiveness of MRI for breast cancer screening in BRCA1/2 mutation car...

Pataky(Reka),Armstrong(Linlea),Chia(Stephe... BMC Cancer 2013-11-26

...BRCA2 are at high risk of developing breast cancer and, in British Columbia, Canada, are offered screening with both mag...

[Molecular basis of gynecological oncology - TopBP1 protein as the guardian o...

Forma(Ewa),Wójcik-Krowiranda(Katarzyna),Bi... Ginekol Pol 2013-07-25

...BRCA2, have been identified. Recent findings suggest TopBP1 to be a breast and ovarian cancer susceptibility gene. Moreo...

Loss of heterozygosity preferentially occurs in early replicating regions in ...

Pedersen(Brent S),De(Subhajyoti) Nucleic Acids Res 2013-11-05

...BRCA2 mutation status. The LOH events are significantly clustered near RNA polII-bound transcription start sites, consis...

BRCA1/2 mutation screening in high-risk breast/ovarian cancer families and sp...

Berzina(Dace),Nakazawa-Miklasevica(Miki),Z... BMC Med Genet 2013-08-26

...BRCA2 mutations including three novel BRCA2 frameshift mutations and one previously known BRCA2 frameshift mutation and ...

The genetics of breast cancer: risk factors for disease.

Collins(Andrew),Politopoulos(Ioannis) Appl Clin Genet 2013-06-19

...BRCA2, a number of rare cancer syndrome genes, and rare genes with more moderate penetrance. A larger group of common va...

Personalized synthetic lethality induced by targeting RAD52 in leukemias iden...

Cramer-Morales(Kimberly),Nieborowska-Skors... Blood 2013-11-07

...BRCA2 genes, and gene expression profiles identifying leukemias displaying low levels of BRCA1 and/or BRCA2. We believe ...

Breast cancer in women aged 25 years and younger.

Dimitrakakis(Constantine),Tsigginou(Alexan... Obstet Gynecol 2013-09-17

...BRCA2 mutations was performed in 12 of 28 young patients and mutations were found in 25% of them. Moreover, young women ...

[Prophylactic surgery in common hereditary cancer syndromes].

Noguès(Catherine),Mouret-Fourme(Emmanuelle... Bull Acad Natl Med 2013-07-17

...BRCA2 mutation carriers. Bilateral prophylactic salpingo-oophorectomy is recommended for BRCA1/ BRCA2 carriers: women wh...

Localization of BRCA1 protein in breast cancer tissue and cell lines with mut...

Tulchin(Natalie),Ornstein(Leonard),Dikman(... Cancer Cell Int 2013-07-24

...BRCA2 (6174delT). We also compared co-localization of BRCA1 and nucleolin in MCF7 cells (wild type) and a mutant BRCA1 c...

A comparison of the detection of BRCA mutation carriers through the provision...

Metcalfe(K A),Poll(A),Royer(R),Nanda(S),Ll... Br J Cancer 2013-11-25

...BRCA2 stipulate that a personal or family history of cancer is necessary to be eligible for testing. Approximately 2% of...

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