Two cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor ...
...BRCA2 mutations or wildtype for both genes. Significantly more foci of TP53 positive cells in histologically normal FTE ...
...BRCA2, PALB2, and BRIP1. To investigate if defects in SLX4 also predispose to breast cancer, the gene was sequenced in a...
...BRCA2 base sequence and for detecting BRCA2 splicing variants and the BRCA2 ORF consensus sequence are useful for better...
...BRCA2 mutation may be helpful for risk assessment and for recommendations regarding prevention. We present an updated an...
Women who have inherited germline mutations of BRCA1/BRCA2 are at increased risk of developing high-grade serous carcino...
Inheriting a BRCA1 or BRCA2 gene mutation can cause a deficiency in repairing complex DNA damage. This step leads to gen...
...BRCA2-containing complex, subunit 3) and Abro1. We have previously shown that Abro1 has a cytoprotective role that invol...
...BRCA2 mutation screening was performed using bi-directional sequencing of all coding exons of BRCA1 and BRCA2. Sequencin...
...BRCA2 deficiency, while exhibiting no impact on cell growth and viability in BRCA2-proficient cells. We now show that th...
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